Analysis The Relation Between Blood Coagulation, Immune Related Index And0Level Diabetes Foot In Traditional Chinese Medicine Syndrome Type

Objective:1. Through60cases in our class0diabetes foot (diabetes foot, DF) patients are average data of traditional Chinese medical syndrome type points, summarizes the class0DF TCM syndrome patients with type distribution rule.2. And check their blood coagulation (PT, ACT, APTT, Fbg, TT), immune (IgM, IgG, IgA, C3, C4) related indicators, and30cases of pure diabetes, diabetes mellitus, DM patients and30cases of normal physical examination (healthy) blood coagulation, immune related indicators for comparison, this paper discusses the different class0DF TCM syndrome type and blood coagulation, immune related indicators, and the relationship with simple DM group, the healthy people compare group.3. The TCM syndrome differentiation for DF patients provides an objective basis, to further improve the Chinese clinical differentiation theory, the early prevention of diabetes foot disease occurrence and further development, reduce amputation rate.Methods:1. According to this study standard, collect our hospital endocrine division0level DF, pure DM patients, medical center of the normal medical clotting, immune index material,0level DF patients basic information, history, symptoms, signs and related inspection results and other material, diagnosis and of TCM syndrome type, etc.2. Summarize class0DF TCM syndrome patients with type distribution rule. 3. Respectively0level detection and simple DF diabetes, the normal physical examination of the blood coagulation indexes, this paper discusses the different class0DF group TCM syndrome types and PT, ACT, APTT, Fbg, TT relationship, with simple and diabetes, and normal compared the medical group, summarizes and analyzes the class0DF group TCM syndrome types and different clotting index of the relationship.4. Respectively0level detection and simple DF diabetes, the physical examination of the normal immune indexes, this paper discusses the different class0DF group TCM syndrome types and IgM, IgG, IgA, C3, C4, and the relationship with simple with diabetes, and normal compared the medical group, summarizes and analyzes the class0DF group TCM syndrome types and different immune index of the relationship.5. According to the case has received various related material, the establishment of database, and the statistical analysis, which count material with X2inspection, many groups by one-way anova is mean differences, the q inspection, and preliminarily the correlation analysis.Results:1. The acquisition cases,0level diabetes foot card type distribution to Yang blood stasis syndrome (38.33%), Yin deficiency and blood stasis (25.00%) and phlegm and blood stasis type winding resistance (23.33%) is more see, among them with Yang, the most common and blood stasis, and qi deficiency and blood stasis (10.00%), liver and kidney deficiency type (3.33%) is a rare.2. In blood coagulation index,0level DF significantly higher levels of PT, and pure DM group (P<0.05), healthy human group (P<0.01) is all have statistical significance;In the class0DF TT reduced significantly, and pure DM group (P<0.05), healthy human group (P<0.05) is all have statistical significance;0level DF group ACT and pure group compared DM, no significant difference (P>0.05),0level DF group, the pure DM group ACT than that of healthy people low (P<0.01, respectively, P<0.05), there is a significant difference meaning;0level DF group and pure DM group, pure DM group and healthy people compare Fbg group there were no significant difference, and class0DF group was healthy people high group, P<0.01, there is a significant difference meaning;Three groups were no significant difference compared APTT. 3. Parting study, liver and kidney deficiency type PT is higher, and blood stasis, Yin Yang and blood stasis, qi deficiency and blood stasis of more statistically significant (P<0.01) are.0level DF group and blood stasis due to the ACT, TT higher than Yin deficiency blood stasis, phlegm and blood stasis type winding resistance, and has a statistically significant (P<0.05, respectively, P<0.01).But five syndrome types of between Fbg, APTT and no obvious difference.4. In immune index,0level DF group and pure DM group, the group compared healthy people, the performance for the class0DF IgM group, IgG, C3, C4than that of pure DM group, the healthy people high group, and P<0.05, all have statistical significance.0level DF group which is pure DM IgA healthy group, the group low, and P<0.05, also has the statistical significance.5.0level DF different card type of immune index, with each card type IgM overall comparison between groups, are all P>0.05, no significant differences.IgG blood stasis highest group in Yin deficiency, qi deficiency and blood stasis group, phlegm and blood stasis group compared winding resistance are significant (both for P<0.01).IgA deficiency in the highest blood stasis group, Yang and blood stasis group, phlegm and blood stasis winding resistance group compared are significant (P<0.01, P<0.05).C3Yin deficiency in blood stasis highest group, and Yang, qi and blood stasis group blood stasis group, liver and kidney deficiency group compared are significant (P<0.01, P<0.05, P<0.05).C4Yin deficiency and blood stasis group average level is Yang, qi and blood stasis group blood stasis group, phlegm and blood stasis, kidney and liver collaterals resistance of deficiency of the group is high, but the comparison between the groups was statistically significant, are all P>0.05, no significant differences.Conclusion:1.0level DF every syndrome type, blood stasis, Yin Yang and blood stasis, phlegm and blood stasis syndrome winding resistance see more, which shows blood stasis syndrome primarily.2. and clotting aspects:0level DF group and pure DM group, the group compared healthy people,0level DF level on the high side of PT, and comparison between groups were statistically significant.0level DF group ACT and pure DM group compared, no statistical significance,0level DF group and healthy human group, pure DM group group compared with healthy people,0level DF group, the pure DM group were lower than that of the healthy people and groups, and all have statistical significance.0level DF group with simple TT group, the DM healthy group, pure DM group group compared with healthy people,0level DF group TT reduced significantly, and all have statistical significance. Tip ACT, TT and diabetes has certain correlation.In the class0DF points in the research of, especially the liver and kidney deficiency type PT rise is most obvious. ACT and the TT in class0DF classification study, qi deficiency and blood stasis highest, Yin deficiency and blood stasis, phlegm and blood stasis type winding resistance is significant, the ACT and the TT qi deficiency and blood stasis type correlation more closely.In diabetes foot every syndrome Fbg type, diabetes foot and comparison between pure diabetes compared with healthy people, the pure diabetes were no difference compared.APTT in diabetes foot every syndrome type, diabetes foot and comparison between pure diabetes comparison, diabetes foot and healthy people, pure and healthy people compare diabetes were no difference compared.The study did not show Fbg, APTT and diabetes and diabetes foot relevance.0level DF exist coagulation system problem, one PT, ACT and the TT and TCM syndrome type between certain correlation.3. immune aspects:0level DF group and pure DM group, the group compared healthy people,0level DF IgM group, IgG, C3, C4than that of pure DM group, the healthy people high group, and P<0.05, comparison between groups were statistically significant. In the class0DF classification study, IgG, IgA, C3are in Yin deficiency and blood stasis rise obvious, shows every type of Yin deficiency syndrome and blood stasis immune dysfunction of the most serious.0level DF immune mechanisms exist the problems, including IgG, IgA and C3and TCM syndrome type between certain correlation.