The Stage I Clinical Research Of The Influence Of TCM Intervention On Lipid Metabolism And The Inflammatory Response

Object ivesThis subject is observed the clinical influence of traditional Chinese medicine used uremia chronic hemodialysis patients microinflammation response and lipid metabolism, to determine the advantage of traditional Chinese medicine on treating micro inflammation and lipid metabolism disorders of the blood dialysis patients. Actively looking for effective ways and means is to improve the blood dialysis patients dialysis quality, life quality, protect the remaining renalfunction, reduce dialysis complications, prolong life, and reduce medical expenses. And the subject provide an objective basis for the future further research and applicationMethodsThe patients were from the blood purification center of Guangdong zhuhai traditional Chinese hospital who were regularly maintaining blood dialysis treatment, randomly divided into two groups:(1)the contor group (20cases):Conventionally maintain dialysis and oral placebo VitB6(2slices/time,3/day);(2)the teatment group(19cases):Conventionally maintain dialysis and oral Chinese medicine(Idose/day).The two groups took medicine for one month. The two groups were tested before and after treatment, including hs-CRP, IL-6, TNF-a,and TCM symptoms points.Resultl.The inflammation index comparison:Comparison of before and after treatment:theHs-CRP IL-6and TNF-a of the teatment group were down after tentment;with statistical significance(P<0.05);the contor group were not down, with no statistical significance(P>0.05). 2. Biochemical index comparison:the teatment group:Alb was no obviously incr ease Before and after treatment, the difference was without statistical significance, TG and TC were down, the difference was with statistical signi-ficance (P<0.05); the contor group:there was no obviously change Before and after treatment, the difference was without statistical significance (P>0.05).3. TCM symptoms points comparison:the teatment group:after teatment the symptoms were better than before teatment, after teatment the TCM symptoms points were less than before teatment, the difference was with statistical significance (P<0.05); the contor group:the symptoms were no obviously change Before and after treatment, the difference was without statistical significan-ce (P>0.05).4. side effects:the teatment group:1case was exited, because he was high potassium medicine hematic disease after5days, the potassium was6.2mmol/L. the contor group:2cases appeared diarrhea after taking the first medcin-e, while diarrhea disappeared after removing rhubarb, so the case could continue treated and observed. There were no side effects on Other patients. The observ-ation were completed39cases.Conelus ion1.The renal failure drop turbidity formulae work for MHD patients, it can imporove their micro inflammation response and lipid metabolism.2.The renal failure drop turbidity formulae can imporove MHD patients’ TCM symptoms and the quality of life.3. The renal failure drop turbidity formulae is Safe, convenient and with few side effects. It is worthy to furtherly investigate on improving mainten-ance hemodialysis patients (MHD) micro inflammation status.