Analysis On The Correlation Between CT Signs And Pulmonary Function Tests In The Evaluation Of Pulmonary Interstitial Fibrosis

Objective:Pulmonary fibrosis is an outcome of interstitial lung disease or end-stage pathological changes, is characterized by the aggregation of fibroblasts and collagen deposition. The most regular means of clinical examination are high-resolution CT scans and pulmonary function tests. HRCT is the best means of providing pulmonary microstructure and strongly associated with pathologic diagnosis. The purpose of study is to recognize the HRCT findings and evaluate the correlation between HRCT findings and pulmonary function tests in pulmonary fibrosis, to study the CT used to provide the basis for assessment of lung injury.Material and Method:31cases were enrolled according to the international diagnostic criterion of pulmonary interstitial fibrosis. All patients underwent CT and pulmonary function tests. The primary HRCT findings were recoded including①ground-glass opacities,②interlobular septal thickening,③interlobular interstitial thickening,④honeycombing andd⑤enlarged mediastinal lymph nodes. A scoring system was adopted to evaluate the CT findings. The pulmonary function parameters including FVC, FEV1, MVV, RV, TLC, FEV1/FVC, RV/TLC and DLco. All the data of HRCT scores and pulmonary function parameters were statistical analyzed by SPSS. The results were expressed asMean±standard deviation.Agreement or discordance of HRCT and PET were analyzed with Spearman’s correlation, p<0.05were defined as threshold for statistical differences and p<0.01were significant differences. Result:In31cases the primary HRCT findings were ground-glass opacities in8cases, interlobular septal thickening in14cases, interlobular interstitial thickening in14cases, honeycombing in13cases, pleural thickening in28cases, Performance can occur over several cases in the same.31cases except one case of pulmonary function tests were normal, the remaining30patients had varying degrees of restrictive ventilatory dysfunction. Lung injury in13cases of mild, moderate lung injury in9cases, severe lung injury in8cases. The results showed that FVC、FEV11、 DLco was negative correlated with CT scores.Conclusion:There are significant correlations between HRCT findings and pulmonary function parameters. The CT score can reflect the pulmonary function changes. Interstitial pulmonary fibrosis and lung CT score showed injuries consistent, CT can be applied to a certain extent, assessment of lung function.