| Purpose:To observe the therapeutic effect of jiangni-humo recipe in treating gastro-esophageal reflux disease(GERD).Methods:A randomized,doubled-blind and controlled trial was conducted.109patients with t gastro-esophageal reflux disease were randomly divided into two groups. In the trial group55patients (n=55) were treated with jiangni-humo recipe combined with omeprazole and in the controlled group54patients (n=54) were treated with Omeprazole, two month being a course of treatment. The observed indexes included curative effect indexes(such as Clinical symptom and Healing of esophageal mucosa) and safety indexes(such as routine urine, blood test, the function of live and kidney, and harmful reaction.)Results:jiangni-humo recipe combined with omeprazole was able to ameliorate the clinic symptoms of the patients in the trial group obviously compared to the control group (P<0.05). Meantime, the patients’Damaged esophageal mucosa was significantly improved compared with before treatment. And the relapse rate of patients in group A was significantly lower。Conclusion:jiangni-humo recipe has surely curative effect in treating t gastro-esophageal reflux disease. It is worth being studyed deeply and developed further. |
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