Evaluation Study On The Effect Of Preventing Hepatitis B Action Program In Liaocheng In2009

BackgroundHepatitis B is caused by Hepatitis B virus, and mainly leads to liver damage. It is easy to convert to chronic hepatitis, cirrhosis and liver cancer. Now in China about10percent of the population is HBV carriers and liver damages appear in1/3of them. The transmission route of Hepatitis B is through blood, mother to fetus and sex. In2006, the positive rate of HBsAb of people between1and59is50.09%, the virus carrying rate of HBsAg is7.18%. The rates in Shandong province is respectively24.26%and3.39%. The occurrence of Hepatitis B is high in Liaocheng City, the incidence rate of2007and2008is respectively68.12/100000and68.35/100000, and85%of the cases are between15and55. The hepatitis B vaccination is the best measure to prevent and control Hepatitis B. To achieve the aim of Hepatitis B prevention and control, Liaocheng City started the preventing Hepatitis B action programme in2009.ObjectiveThe purpose of the study is to understand the prevalence of Hepatitis B in different populations and areas in Liaocheng City, to evaluate the effect of Hep B vaccination in local area and to discuss the risk factors of local group infected with Hepatitis B.MethodsMultistage sampling was used to get the sample. Questionnaire was used to get age, sex, nation, career, address, income, height, weight, immune history, infection history, family history, chronic diseases history, smoking history and drinking history of the population. We collect, transport, dispose and analyze the serum sample. We use the software of SPSS16.0to analyze the data.ResultsBefore the peventing Hepatitis B action programme we surveyed2526people and after2491. The number of HBsAg (+) is73, and the positive rate is2.89%. HBsAg (+) people are mainly between15and55years old. Univariate unconditional logistic analysis shows that the differences of the four factors of living with HBsAg (+) people, blood transfusion, paid blood donation and low income are significant. Multivariate unconditional logistic analysis shows that living with HBsAg (+) people, paid blood donation and low income are risk factors of Hepatitis B. The difference of the HBsAb positive rates before and after the programme is significant. The difference of male HBsAb positive rates before and after the programme is significant; so is female. Before the programme, the HBsAb positive rate of0～14age group is the highest (56.85%), and group above60is the lowest (34.38%). With the growth of the age, the HBsAb positive rate is declining, and the difference is significant. After the programme, the HBsAb positive rates of all the age groups, career groups and income groups increased. In different career groups, the index of peasants increases the most; and in different income groups, the the positive rate of people whose incomes were below3000per year increase the most. And the differences are all significant.The number of both HBsAg (-) and HBsAb (-) is849. After the vaccination,670people converts to HBsAb (+). The vaccination success rate in Gaotang, Shenxian and Dong’e is respectively100%,84.04%and62.25%. The differences of the3places are significant. The vaccination success rate of people between26and35is the highest and that of45-55and people above56are the lowest. The difference of different age groups is significant. The vaccination success rates of male and female are respectively78.88%and78.95%. There is no significant difference.Conclusions and Suggestions According to the results and discussion, conclusions and suggestions were put forward as follows:1.Living with HBsAg (+) people, paid blood donation and low income are risk factors of Hepatitis B in local area.2. After the Hep B vaccination, the HBsAb positive rates in age, sex, career and income all increased. In different careers, the positive rate of peasants increase the most; and in different incomes, the positive rate of people whose incomes were below3000per year increase the most.3. Hepatitis B vaccination for susceptible population is effective methods to prevent Hepatitis B. lit could also increase the longevity and improve the life quality of the population.4. More attention should be paid to health education of Hepatitis B knowledge and Hep B vaccination in health people. Vaccination of Hep B in healthy people could reduce the Hepatitis B incidence and is very important to advance the physical constitution of all the population of the country.