Inheritance And Innovation Of The Academic Thought Of Professor Han Bailing And The Clinical Experience Of Yan Lingdan For Premature Ovarian Failure

Objective:Carry forward for the inheritance of better guide clinical practice, Mentor Professor Han Yanhua in the heritage of Mr. Han Bailing " the hepatorenal doctrine " because of academic thought on the basis of different diseases with different diseases ", development Han the gynecological unique academic style, clinical application of the extension panacea treatment of kidney deficiency with premature ovarian failure. In this paper the clinical efficacy observed extension of panacea to the treatment of kidney yin with premature ovarian failure, and to explore the extension of a panacea treatment of kidney yin with premature ovarian failure mechanism, sum up the clinical experience of the mentor Professor Han Yanhua treatment of this diseaseMethods:The subject has literature and clinical research into two parts.literature:collects and systematizes the ancient medical books,use statistics to analyze the etiology and pathogenesis of premature ovarian failure, treatment principles, drug laws of ancient physicians.Read,collects and systematizes books, papers and manuscripts each period of Professor Han Bailing with retrospective study methods,summarized his clinical experience in treatment of premature ovarian failure and features of the theory.Clinical Research:The20cases of40cases kidney deficiency type POF patients were divided into treatment group(yanling mini-pills),the remaining20cases were divided into treatment group(liuwei dihuang pills) by access to random number table.Observe the clinical symptoms,change of FSH,LH,E2before and after treatment.Observe the differences of the treatment group and control group after treatment.Recsult: 1.In all of etiology and pathogenesis of premature ovarian failure, the kidney essence deficiency type accounting for19.6l%;followed by the liver-kidney accounted for17.64%.2.Premature Ovarian Failure replenishing drugs type, frequency, were among the first, involving drugs17, frequency182, a requency of56.01%; followed is liqi drug, an overall frequency of43times, frequency, accounting for15.23%; Qingrexiehuo drugs, with a total frequency of21times, frequency, accounting for6.45%. Description replenishing drugs is the main drug treatment of mature ovarian failure3.In the integrated effect:the treatment group,20patients recovered in2cases,9cases marked effective, effective in4cases,5cases noneffective, the total effeetive rate was80%, control group,20patients recovered in7cases,6cases marked effeetive, effeetive7cases,7cases noneffective, the total effeetiverate was65%, but the total effete compared the two groups were not significantly different(P<0.05), shows that the integrated effeets between Yanlingdan and the control group are no significant difference.4.In improving the TCM syndrome areas:pre-treatment in patients with waist and knee pain, dizziness, tinnitus, night urinary frequency, malaise fatigue and other symptoms are significantly improved after treatment, the treatment group in improving the waist and kneepain, dizziness, tinnitus, night urinary frequency and malaise fatigue and other symptoms are better than thecontro group.5.In the menstrual recovery:the treatment group20cases regular menstrual1cases, two or more times within six months of the8cases,one times within six months of5cases,6casea of amenorrhea, menstrual recovery rate is70%;20patients in the control group, regular menstruation5cases,two or more times within six months of the4cases, one times within six months in cases,11ceases, are still the two ceases of amenorrhea, menstrual recovery rate is45%, there no significant difference between the two groups(P<0.05).6. In serum reproductive endocrine hormones areas:the two groups of FSH are decreased after treatment,compared with pre-treatment the difference is significant(P<0.05)),shows that the treatment group and control group are effcetive;the two groups after treatment,, the two groups after treatment, control group FSH levels is decreased significantly compared to the treatment group, the difference is significant(P<0.05), the two groups FSH level are both inereased, the re are no significant difference(P>0.05).7.Detection in safe and adverse reaetions:the treatment group and the control group has no adverse reactions.Conclusion:1. Kidney disease is a major factor in premature ovarian failure, heart and kidney dysfunction, liver and spleen on each other. Qixuand bloodyu is an important factor in the incidence of premature ovarian failure.2.By drug efficacy, and the emergence of Meridian frequency, obtained the basic idea of premature ovarian failure treatment and medication methods:Kidney-based, combined Jiangpiyangrong heart, nourishing the liver is stressed the main treatment for premature ovarian failure.3. Yanlingdan not only to cure premature ovarian failure patients significantly improved clinical symptoms, and safety without side effects, is an effective treatment of premature ovarian failure yin-type drugs.4.Yanlingdan treatment of premature ovarian failure may be extended by regulating the reproductive endocrine hormones in serum FSH, LH, E2levels achieved.