An Survey On The Prevalence Of Nonalcoholic Fatty Liver Disease Residents In Kelamay Xinjiang

Objective: To investigate the prevalence of nonalcoholic fatty liver disease (NAFLD)among residents based in kelamayi xinjiang, analyze its epidemiological and risk factorsand discusses the relationship between the prevalence and the metabolic syndrome，provide the basis for cause prevention. Methods: Using the current study, we analyze2858subjects who underwent a healthy checkup and all the residents galactic communityduring April to June2010with general information, anthropometric measurements, andbiochemical parameters. The diagnosis of fatty liver disease was carried byultrasonography. Results:(1) Among2858residents in kelamayi xinjiang,1043peoplewere affected the nonalcoholic fatty liver disease,the total detection rate was36.49%. Theprevalence of NAFLD in female and male were28.74%and41.34%, the prevalence ofNAFLD in male was significant higher than female, the difference was statisticallysignificant (P <0.05). The prevalence of NAFLD in Uygur nationality was35.68%and itwas27.03％in Han nationality, the difference was statistically significant (P <0.05). Indifferent gender, the nonalcoholic fatty liver disease rates of Uygur nationality was higherthan the han nationality, the difference was statistically significant (P <0.05).It appears asignificant difference on the prevalence of NAFLD between Uygur nationality and Hannationality in any groups, except the50~60age group(P<0.05). In the differentoccupational groups, such as professional and technical personnel、administrative staff、workers and individuals, it appears a significant difference on the prevalence of NAFLDamong Uygur nationality and Han nationality. In the different cultural levels, such asuniversities and more than high school or college、 junior high school or secondary schooland illiterate, it appears a significant difference on the prevalence of NAFLD amongUygur nationality and Han nationality;(2)NAFLD group’s fasting plasma glucose(FPC)、uric acid (UA)、alanine amiontransferase (ALT)、aspartate aminotransferase (AST)、triglyceride (TG)、cholesterol (CHO)、low density lipoprotein-cholesterol (LDL)-C)、bodymass index (BMI)、waistline、waist-hip ratio (WHR)、 systolic and diastolic blood pressure were higher than the normal people (P <0.05), however, high densitylipoprotein-cholesterol (HDL-C) level was below the normal people (P <0.05). Theprevalence of NAFLD in objects which had overweight and(or) obesity、central obesity、high blood pressure、diabetes、hyperlipidemia、high uric acid hematic disease、abnormalof transaminase and γ-glutamyl transferase (GGT) were significantly higher than inobjects without these symptoms. After further logistic regression analysis, it indicated thatBMI、WHR、TG、age、FPC、LDL-C、ALT、 gender and UA were risk factors to induceNAFLD. Conclusion: There was a higher rate of nonalcoholic fatty liver disease inkelamayi Xinjiang. Obesity and metabolic disorders were closely with NAFLD. Weshould changes the lifestyle, control weight, correct metabolic disorder to reduce theprevalence of NAFLD.