| Objective: To observe the effect of Bushen Xiaozheng decoction for treatment ofdeficiency of kidney and blood stasis type of endometriosis in clinical curative effect, andto explore its mechanism, providing science basis for its clinical application. Methods:60patients with kidney deficiency and blood stasis endometriosis patients were randomlydivided into treatment group (30cases, oral Bushen Xiaozheng party), control group (30cases, oral Hongjinxiaojie concentrated pill), in the7days before, use drug10dayscontinuously,3menstrual cycles for a course of treatment. Comparison of the analgesiceffect of two groups before and after treatment, clinical efficacy (mass narrow extent) andblood rheology indexes, serum cancer antigen125(CA125), serum anti endometrialantibodies (EmAb) and the changes of. Results: the treatment group and the controlgroup the clinical total effective rate were96.67%,63.33%, two groups had significantdifference (P <0.01); in the analgesic effect, two groups of the total efficiency ofrespectively96.67%,76.67%, two groups had significant difference (P=0.01). Aftertreatment of hemorheological indices were obviously improved (P <0.05), the treatmentgroup in the reduction of blood high cut, the blood low shear viscosity, plasma than incontrol group (P <0.05).B ultrasound in gynecology: adnexal mass was significantlyreduced (P <0.01), CA125, EmAb decreased significantly (P <0.01), between the groupshad significant difference (P <0.01or P <0.05). In the testing process without obviousadverse reaction. Conclusion: tonifying kidney deficiency and blood stasis eliminatingdisease and method for treatment of endometriosis, with good pain relief and the overalladjustment function. Its mechanism of action may be related to the decrease of bloodviscosity, blood vessel protecting vascular endothelium, promote blood circulation; improve pelvic bloodcirculation; regulation of ovarian hormones, regulation of endogenous analgesic substancesynthesis rate. |
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