The Retrospective Analysis On Metabolic Syndrome And Its Related Factors Of Retired Cadres In The City Of Changchun In Jilin Province

Objective: To learn the prevalence of MS and observe its age present trends and related risk factors on more than60-year-old retired cadres in Changchun, Jilin Province.Methods: After statisticsing5consecutive years medical data of537more than60-year-old retired cadres from the Medical Center of FirstClinical Hospital in Jilin University, including the results of the questionnaire, general physical examination, and blood tests, ECG and other tests.Through the use of SPSS17.0to learn the prevalence of MS and observeits age present trends and related risk factors on the elderly population,to analyze the relationship between MS and hypertension, diabetes, positive urine protein, fatty liver, cerebral infarction,to figure out the correlation smoking,moderate alcohol consumption, quality of sleep, exercise,drugs and so on.Results: The average value of WC,DBP, TC, LDL-C, TC are declining from the first to the fifth year,at the same time,the average valueof BMI,SBP, FBP,UA and HDL-C are gradually increased with the growth of the age.In addition,the average value of WC,TC in the first yearare higher than the fifth year(P <0.05),and he average value of BMI,FPG,HDL-C are lower than the fifth year(P <0.05).From the study,we cansee that the peak of MS prevalence is60-69group in the populationover the age of60years,and the prevalence of MS shows a downwardtrend with the growth of age.From the first to the fifth year,the prevalence of MS respectively are higher than the other two groups. The prevalence of hypertension in MS group are77.17%,77.11%,81.71%,79.43%,84.21%from the first to the fifth year.Rather than the MS group,t he prevalence of hypertension in non-MS group are53.82%,55.8%,53.31%,56.91%,62.34%from the first year to the fifth year. The prevalence of hypertension in the MS group are distinctly higher than the non-MS group(p <0.001), and which show an upward trend with the growthof age.The prevalence of T2DM from the first to fifth years are:34.24%,37.95%,34.86%,34.29%,37.5%, and show an upward trend withthe growth of age,the prevalence of T2DM in non-MS group are:9.92%,11.05%,12.98%,14.36%,15.84%from the first year to the fifth year,and the prevalence of T2DM show an upward trend with the growthof age,moreover,compare to the non-MS group,the prevalence of T2DMin the MS group are higher apparently(p <0.001),the statistically differences are significantly.Similarly,the prevalence of fatty liver in the MS group are47.83%,27.71%,40.57%,49.14%,65.79%from the first to thefifth year, rather than the MS group,the prevalence of fatty liver in non-MS group are14.73%,5.93%,14.09%,12.43%,21.3%from the firstyear to the fifth year. We can find that the fatty liver prevalence in theMS group are significantly higher than the non-MS group(p <0.001),inaddition,the prevalence of fatty liver is gradually increased with the growth of age.The prevalence of positive urine protein and cerebral infarction in MS group are higher than those in non-MS group, but both thetwo disease prevalences in two groups respectively showed no statistically significant differences.The regression analysis in MS shows that the riskfactors of MS include BMI(2.33,95%CI:2.16-2.52), MAP (1.04,95%CI:1.03-1.05), FPG (1.44,95%CI:1.33-1.56), TG (1.97,95%CI:1.67-2.31), fatty liver (1.88,95%CI:1.45-2.44), but the moderate alcohol consumption（0.91，95%CI：0.65-1.27) and the exercise (0.84,95%CI:0.61-1.15) are protective factor for MS.Conclusion:1.The average value of WC,DBP, TC, LDL-C, TC aredeclining from the first to the fifth year,at the same time,the average va lue of BMI,SBP, FBP,UA and HDL-C are gradually increased with thegrowth of the age.2.The peak of MS prevalence is60-69group and theprevalence of MS shows a downward trend with the growth of age inthe population over the age of60years.3.The disease MS can increasethe prevalence of hypertension,T2DM,fatty liver,urine protein and cerebral infarction,and the prevalence of hypertension,T2DM,fatty liver,urineprotein and cerebral infarction are gradually increased with the growthof the age.4.To the disease MS, the BMI,MAP, FPG, TG and fatty liverare the risk factors, but the moderate alcohol consumption and the exercise are the protective factor.