The Evaluation Of The3.0T MRI Diffusion Weighted Imaging On The Diagnosis And Treatment Of Cervical Cancer

Objective: Explore the advantages of magnetic resonance diffusion-weightedimaging combined with conventional MRI examination in the diagnosis and stagingof cervical cancer,And short-term assessment of the efficacy of cervical cancer afterradiotherapy and chemotherapy.Method：The study of50cases were collected from patients with cervical cancer,uterine disease in patients with a total of15cases, all cases were cervical smears,biopsy or surgery and pathology.Cervical cancer patients according to clinicaltreatment group of30patients divided into surgery and chemotherapy group of20cases, all patients were performed conventional MR and DWI scans, analyze routineMRI and DWI features can and apparent diffusion coefficient （ADC） values.Comparison of cervical cancer and normal cervical mean ADC values; Cervicalcancer of different pathological type and different differentiation degree of the meanADC values; Image stage of cervical cancer patients with pathology contrast, theassessment of the accuracy of conventional MR combined with DWI installmentsï¼›Chemotherapy group of20patients at the end of treatment after a routine MR andDWI examination, were used to measure put before chemotherapy, the mean ADCvalue of the two groups after treatment after CR group and PR group mean ADCvalue, the above dataresults were compared with analysis.Results：1、Normal cervical inner zone, combined and packed three-layer structure ADCvalues were （1.63±0.24）×10^-3mm²/s、（1.40±0.12）×10^-3mm²/s、（1.86±0.22）×10^-3mm²/s，Combined signal and ADC values were lower than the rest of thetwo-tier, three-tier structure, the mean ADC value （1.62±0.25）×10^-3mm²/s.2、50cases of cervical cancer ADC value （0.95±0.16）×10^-3mm²/s, cervicalcancer ADC values were significantly lower than the normal the cervix average ADCvalue, the difference was statistically significant （P <0.05）. ADC value of cervical squamous cell carcinoma and adenocarcinoma （0.91±0.22）×10^-3mm²/s and（0.89±0.20）×10^-3mm²/s, the difference was not statistically significant （P>0.05）.Cervical cancer various degrees of differentiation ADC values were:middle-high-differentiated group（0.96±0.14）×10^-3mm²/s， poorly differentiated group（0.89±0.12）×10^-3mm²/s, the difference was statistically significant （P <0.05）.3、30surgeries conventional MRI staging the conventional MR binding DWIstaging and pathological findings, the accuracy rate was90%（27/30）,96.7%（29/30）.MR images of20patients with chemotherapy group credits with clinical stagediagnosis rate was75%（15/20）. Pathologically confirmed pelvic lymph nodemetastasis in18cases, the MR detection （short diameter>1cm）16cases,2cases ofmisdiagnosis.4、ADC value of cervical cancer after radiotherapy and chemotherapy wereincreased, radiotherapy and chemotherapy before and after mean ADC values were（0.87±0.20）×10^-3mm²/s,（1.42±0.16）×10^-3mm²/s. The difference was statisticallysignificant （P<0.05）,12patients with CR group and8patients with mean ADC valueof the PR group （1.40±0.18）×10^-3mm²/s,（1.12±0.15）×10^-3mm²/s, the differencewas statistically significant （P<0.05）.Conclusion：DWI able to distinguish between normal cervix and cervical cancertissues, no significant relationship between the quantitative indicators of the ADCvalue and pathological types of cervical cancer, but with a certain degree of tumordifferentiation suggestive and can monitor cervical cancer radiotherapy andchemotherapy response. The, DWI therefore short-term efficacy of cervical cancerdiagnosis, predict pathological differentiation, staging and evaluation of great value.