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Study Of The Dilated Cardiomyopathy Heart Failure Of TCM Syndromes’s Distribution Characteristics And It Correlation Of NT-proBNP, LVEF

Posted on:2014-01-11Degree:MasterType:Thesis
Country:ChinaCandidate:T CaiFull Text:PDF
GTID:2234330398953694Subject:Internal medicine of traditional Chinese medicine
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Objectiveto analyze the distribution characteristics of Chinese medicine syndrome in patients with dilated cardiomyopathy heart failure and its relationship with Cardiac function,NT-proBNP, LVEF,Learning DCM patients with heart failure distribution characteristics of Chinese medicine syndrome and syndrome elements,And to provide a reference index of Chinese medicine dialectical type and severity of illness.Methodswe collected firsthand clinical data of86patients with DCM they hospitalized Cardiology of Wuhan Tong ji Hospital in2011-02to2012-06.these patients with heart failure as the main performance. Classified86patients with DCM its dialectical type,determined their cardiac function, measured the levels of plasma’s NT-proBNP by radioimmunoassay, determinated the levels of LVEF by siemens Doppler ultrasound. analysed the statistical by SPSS16.0software.Results 1. The single Chinese medicine type of DCM are the main exist as Qi deficiency and Blood stasis Where qi deficiency exists in each patient,The frequency of single syndrom in the patients with DCM: Qi deficiency (100%)> Blood stasis (75.58%)> Yang deficiency (69.77%)> Water retension (59.30%)> Yin deficiency (41.86%)> Phlegm (29.07%).2. DCM patients with different syndromes the distribution of its TCM single permit:Patients with qi collapse of lung and heart syndrome are Qi deficiency based, deficiency of qi and yin syndrome are Qi deficiency and yin deficiency based,qi collapse and blood stasis syndrome are Qi deficiency and blood stasis based, yang collapse of heart and kidney syndrome are Qi deficiency and yang deficiency based,yang collapse and fluid-retention stagnation syndrome and phlegm in lung syndrome patients in critical condition,the complexity of the clinical symptoms,many Card prime Exist.3. In Syndrome element combination most of qi collapse of lung and heart syndrome patients with a single syndrome elements in Syndrome element combination,deficiency of qi and yin syndrome patients presented with two cards prime,yang collapse of heart and kidney syndrome and qi collapse and blood stasis syndrome patients are the three certificates prime, the prime of the four cards, yang collapse and fluid-retention stagnation syndrome and phlegm in lung syndrome patients in critical condition,the complexity of the clinical symptoms,There are four cards prime, Five Card prime and six Card prime.4. Chinese medicine dialectical type frequency as follows:yang collapse of heart and kidney syndrome> yang collapse and fluid-retention stagnation syndrome>qi collapse and blood stasis syndrome> phlegm in lung syndrome> deficiency of qi and yin syndrome>qi collapse of lung and heart syndrome.5. Heart Association functional class with the qi collapse of lung and heart syndrome、deficiency of qi and yin syndrome、qi collapse and blood stasis syndrome、yang collapse of heart and kidney syndrome、yang collapse and fluid-retention stagnation syndrome、phlegm in lung syndrome in ascending order.6. The content of NT-proBNP ascend in order from Chinese medicine dialectical type which is qi collapse of lung and heart syndrome; deficiency of qi and yin syndrome; qi collapse and blood stasis syndrome; yang collapse of heart and kidney syndrome; yang collapse and fluid-retention stagnation syndrome and phlegm in lung syndrome. And the front four groups compare with any groups of the after two groups which has statistically significant (P<0.05).7. The content of LVEF decrease in order from Chinese medicine dialectical type which is qi collapse of lung and heart syndrome; deficiency of qi and yin syndrome; qi collapse and blood stasis syndrome; yang collapse of heart and kidney syndrome; yang collapse and fluid-retention stagnation syndrome and phlegm in lung syndrome. And the after four groups compare with any groups of the front two groups which has statistically significant (P<0.05).ConclusionsThe single Chinese medicine type of DCM are the main exist as Qi deficiency and Blood stasis Where qi deficiency exists in each patient; DCM patients with the syndrome elements increase exacerbations. The distribution of DCM Chinese medicine dialectical type has no obvious features, yang collapse of heart and kidney syndrome most frequently, qi collapse of lung and heart syndrome at least; NT-proBNP, LVEF in patients with DCM can be used as a reference index of Chinese medicine dialectical type and severity of illness.
Keywords/Search Tags:Dilated cardiomyopathy, Syndrome elements, Chinesemedicine dialectical type, NT-pro BNP, LVEF
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