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Analysis Of Clinical Characteristics Of The Diabetic Foot Lower Extremity Arterial Disease

Posted on:2014-01-18Degree:MasterType:Thesis
Country:ChinaCandidate:K ZhangFull Text:PDF
GTID:2234330398991818Subject:Traditional Chinese Medicine
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Objective: This issue through clinical data of patients with lowerextremity atherosclerotic disease (LEAD) were studied retrospectivelysummary of the analysis of the diabetic foot (DF) and non-diabeticarteriosclerosis obliterans (ASO) cases of lower extremity arterial diseasedistribution clinical features, and further clinical symptoms of DF correlationanalysis with below-knee artery lesions in installments, in order to provide thenecessary basis for the clinical revascularization.Methods: The first part of the select Hebei Province Traditional ChineseMedicine Hospital surgical and Xiyuan Hospital of China Academy ofTraditional Chinese Medicine Vascular Surgery October2010-October2012admitted130patients with diabetic foot and non-diabetic patients witharteriosclerosis obliterans72, respectively, define Group I and Group II,collected into groups limb arterial CTA and/or DSA results, iliac, femoral,popliteal, below-knee arteries segmentation method limb single segmentbetween the two groups, double segment, and more segmental arteriesinvolving statistical analysis. The lesion data registered under the lesionclassification statistical analysis. The second part of the select Hebei ProvinceTraditional Chinese Medicine Hospital surgical and Xiyuan Hospital of ChinaAcademy of Traditional Chinese Medicine Vascular Surgery October2010-October2012admitted only a unilateral infrapopliteal artery lesions inpatients with diabetic foot100, defined as Group III, collected the clinicalsymptoms, ABI values and biochemical parameters, infrapopliteal arterylesions, including statistical analysis between the anterior tibial artery,posterior tibial artery, peroneal artery and plantar artery ring involving eachindex. Results:1、130patients with diabetic foot (DF) patients (250limbs,711lesions)and72patients with non-diabetic arteriosclerosis obliterans (ASO) patients(132limbs,262lesions) into the first part of the study.①DF limb singlesegment, double segment, multi-segment arterial involvement rate was49.20%,27.2%and23.6%, respectively, while the ASO limb were45.45%,33.33%and21.21%, two different sets of segmental arteries constitute twosets of single-segment lesions below-the-knee arteries involving rate than nostatistically significant difference(P>0.05), a statistically significant difference(P<0.05), two double segment disease shares of infrapopliteal arteryinvolvement rate a statistically significant difference (P <0.05), two sets ofmulti-segmental lesions femoropopliteal below-knee artery involvement wasno statistically significant difference (P>0.05).②DF limb femoral arterysegment and infrapopliteal arterial segments compared with iliac artery andpopliteal artery involving a high proportion compared statistically significantdifferences (P<0.05), the ASO limb femoral artery segment, and poplitealartery segment iliac artery and below-the-knee artery involving a highproportion of each group compared to a statistically significant difference(P<0.05).③DF13.60%of the limb iliacartery segment lesions,40.08%ofthe limb femoral artery segment lesions,26.80%of the limb popliteal arterysegment lesions, the ASO were34.09%,14.91%,37.88%, and the two groupsiliac, femoral, popliteal artery segment lesions involving both a significantdifference (P<0.05). From the two groups iliac, femoral, popliteal artery lesiondistribution on the statistics, there are also significant differences (P<0.05).④DF limb below the knee to artery lesions involving rate of95.20%, and bothhave significant differences (P<0.05) as compared with the the ASO limb28.79%infrapopliteal arterial lesions involving rate DF limb Total lesion711ASO limb lesions262the lesions two groups were70.74%and23.28%of thelesions artery in the knees, a significant difference (P<0.05).⑤in DF limb,involving below the knee arteries of503(70.74%), many of them involvingthe anterior tibial, posterior tibial artery, peroneal artery less involved, statistically significant differences (P<0.05).⑥≥2artery disease in twobelow-knee artery lesions, respectively31.58%and69.75%, statisticallysignificant differences (P<0.05).2、100cases only a unilateral below-knee artery disease in diabetic footpatients (100limbs) move on to the second part of the study. Below-kneeartery a diseased limb, below-knee limb arterial lesions2below-knee limbartery lesions3clinical symptoms (intermittent claudication, rest pain, footulcers or gangrene) ABI value and Biochemical indicators (TG, HDL, LDL,HCY, ACE, CRP) on the existence of a significant difference (P<0.05), countthe more, the more severe clinical symptoms, the lower the value of ABI, Themore blood lipids, vascular media involvement with the below-knee arteries,inflammation indicators deviate from the normal. Installments according toFontaine, plantar artery ring lesion incidence Phase III, Phase IV limbcompared with the phase II limb statistically significant difference (P<0.05).Conclusion:1Diabetic foot lower extremity arterial disease as the main performancemulti-plane arteriosclerosis obliterans, involving up the femoral artery andinfrapopliteal arteries.2Diabetic foot lower extremity arterial disease involving the theinfrapopliteal small artery, but not diabetic arteriosclerosis obliteranspredilection in the lower limbs, medium-sized arteries, such as the iliac artery,femoral artery and popliteal arteries, etc.3In the pathogenesis of diabetic foot lower extremity arterial tibialisanterior and posterior tibial artery involvement, the peroneal artery lessaffected.4Patients with diabetic foot below the knee artery artery disease multipleviolations of more than two.5Diabetic foot below the knee arterial lesions involving count the more,the more severe clinical symptoms, ABI lower, lipid metabolism disorders,abnormal vascular media heavier inflammatory response.6The lower limbs of diabetic foot a heavier clinical symptoms, the higher the incidence of plantar artery ring lesions.
Keywords/Search Tags:diabetic foot, arteriosclerosis obliterans, CTA and/or DSA, lesions involving characteristics, below-knee artery lesions
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