590 Cases Of Chronic Hepatitis B Alt Or 2 X Uln Combine Traditional Chinese And Western Medicine Treatment Effective Cases Symptoms Characteristic Of Traditional Chinese Medicine Research

Background:Chronic hepatitis B is a chronic infectious disease caused by infection with the hepatitis B virus(HBV), and is popular in the world, which is one of problems to be solved. In China, the incidence of chronic hepatitis B is high. The2006survey shows that people in the1-59age phase of HBsAg carrier rate of7.18%and it is estimated that about20million persons with the chronically infection of HBV. chronic hepatitis B and liver cirrhosis, hepatocellular carcinoma is closely related,which is a serious threat to the one or more generations of human life. Therefore, to slove the problem of the treatment of chronic hepatitis B must be without delay.In recent years, the main treatment of chronic hepatitis B contains Traditional Chinese medicine(TCM) and modern medicine and integrative medicine. The most important treatment of modern medicine is antiviral,and the nucleoside analogues for the treatment is the hot spot, Such as adefovir dipivoxil lamivudine,entecavir etc. However, the shortcomings of the nucleoside analogues are resistance and mutation. Research indicates that the TCM treatment of chronic hepatitis B is good at regulation of the immune, anti-inflammatory and protection of liver function liver, and there is a substantial research shows that TCM in nucleoside analogue resistance mutations appears on a certain therapeutic effect. In recent years, integrative medicine research deeply. The eleventh-five topics of chronic hepatitis B Syndromes and integrative medicine treatment options (ALT≥2ULN)"TCM" liver depression and spleen, liver and gallbladder damp heat "compound syndrome in patients with chronic hepatitis B for the research population. Chinese herbal formula+adefovir dipivoxil as trials drug, adefovir dipivoxil, a single as the control drug, in order to explore the TCM and morden medicine combined with therapy.This thesis based on the Eleventh Five-Year collection cases, in order to understand and explore the Integrative Chinese medicine symptoms characteristic of the advantages of the treatment of chronic hepatitis B patients.Objective:To explore the application of effective treatment of chronic hepatitis cases of TCM symptoms characteristic of Integrative Medicine and trends showing improved characteristics.Methods:The main object of studying of590cases after After48weeks of treatment, HBeAg and HBV-DNA at the same time was negative, aminotransferase normalization cases and48weeks of non-negative test group cases. The nimodipine method efficacy evaluation of TCM symptom improvement using the X2test to compare effective cases of the experimental group and control group, the symptoms improve, improvement rate, the rate of change of the statistical description of the valid cases and cases of non-negative Chinese medicine symptom improvement trend characteristics.Results:1The symptoms characteristic of group:48weeks of HBeAg of HBV-DNA was also negative, aminotransferase normalization of the test group of cases into the group of symptoms (symptoms, the proportion of>90%)4than of HBeAg of HBV-DNA negative at the same timetransaminase normalization case-control group and the non-negative test group, symptom clusters and gallbladder damp heat.2. To improve the characteristics of symptoms after treatment:48weeks of HBeAg of HBV-DNA negative at the same time, the group of transaminase normalization case the experimental group improved TCM symptoms, liver and gallbladder damp and liver depression-based, negative HBeAg and HBV-DNA in the same time, aminorransferase normalizationcases compared to controls, improve the symptoms gradually increase over treatment time, more than the control group.Compared with non-negative test group, the improvement of TCM symptoms significantly better than the non-negative test group.Conclusion:Integrative treatment programs dominant symptom clusters improved TCM symptoms of liver depression and hot and humid, compared with the control group than the control group for the hot and humid symptoms improve, compared with non-negative test group,48weeks HBeAg, HBV-DNA negative at the same time, transaminase TCM symptoms of the normal test group improved significantly.