| Purpose:The analysis of the construction and change of all the malignant tumor patients in Yanbian, also the incidence and death of malignant tumors of Yanbian residents can provide basic information for analysis and evaluation of main diseases threatening the health of residents and the main malignant tumor. Meanwhile the result will provide objective basis of implementation and monitoring of key prevention and treatment of chronic diseases, common diseases, and scientific basis for the research and prevention of tumor development in Yanbian.Methods:All of the malignant tumor patients amounting to234897in Yanbian public hospitals for the first time were compiled from January of2005to December of2008.We used international standard ICD-10to classify the malignant tumors, and using SPSS17.0statistical software to evaluate the data. The significant test is done with chi-square test while the trend test adopts the method of regression analysis and descriptive analysis is used to analyze the current description and change of the data.Results:1. From2005to2008, the number of residents suffering the top ten system diseases in Yanbian Prefecture accounted for more than90%of the total disease. During the four years, the constituent ratio of the top10diseases did not change significantly (P>0.05), but all kinds of system diseases changed to some degree. During2006to2008circulatory system diseases accounted for the first, injury, poisoning, exogenous diseases accounted for second. During the four years, the order of the top4diseases (circulation system; the injury, poisoning, external cause; the digestive system disease; pregnancy, childbirth, and the puerperium) scarcely changed. However, the tumor ranked the fifth in the2005and2006, and decreased to the sixth in2007and2008. Endocrine, nutritional and metabolic diseases in2005and2006ranked the ninth and rose to the eighth in2007and2008. Infectious and parasitic diseases in2005and2006ranked the eighth and in2008decreased to the tenth. Muscle, skeletal system, connective tissue diseases ranked the tenth in the first3years and in2008it rose to the ninth.2. From2005to2008, the constituent ratio changed significantly in the top10diseases in Yanbian Prefecture among all the residents staying in the hospital (x2=830.5, P<0.01). During the four years, the hospitalized patients of Yanbian residents with cardiovascular and cerebrovascular diseases have always ranked the first. From2005to2006the first ten diseases had no change. In contrast, from2007to2008they changed significantly. Among them, the fractures ranked the second in2005and2006, third in2007and declined rapidly to the ninth in2008; hypertension and intracranial injury decreased a place. Malignant tumor ranked the third in2005and2006, the fifth in2007and increased to the second in2008; diabetes ranked the eighth in2005and2006, the seventh in2007and increased to the fifth in2008; ischemic heart disease increased from the fourth in2005and2006to the third in2008; pulmonary inflammation increased from thirteenth in2005and2006to the eighth in2008.3. From2005to2008, the top3diseases that accounted for the death in10system diseases of the residents of Yanbian Prefecture circulatory system disease, tumor, diseases of digestive system. Among them, the circulatory system diseases accounted for the first, the three accounted for70%of the sum of diseases that caused the hospitalized death of Yanbian residents. During the four years, the top10diseases that caused deaths have not changed, but the position of them haven’t. Circulatory system diseases and tumor diseases in the sequence of death causes have no change; malignant tumor has always ranked the second. Endocrine, nutritional and metabolic diseases increased from the ninth in2005to the seventh in2008in death; infectious and parasitic diseases of death dropped one place from2005to2006and2008.4. From2005to2008, the top5diseases that caused the death of hospitalized residents in Yanbian didn’t change. The first place is still the cerebral vascular diseases; malignant tumors ranked second and the proportion declined:dropped from18.71%in2005to15.84%in2008, but the trend was not statistically significant. Ischemic heart disease, kidney failure, non-medicinal substances toxic effects of disease death causes decline. In2008, ischemic heart disease ranked the third in the former3years dropped to the fourth, renal failure ranked the sixth from2005dropped to the seventh in2008, toxic effect of non medicinal substances ranked the eighth in2005dropped to the fourteenth in2008. But these diseases that caused death had no significant decline. Diabetes in the rank of death is the seventh in2005rising to the sixth during2006to2008, and the constituent ratio of diabetes increased year by year (R2=0.903, F=18.623, P=0.05). In addition, intracranial injury, bronchitis and emphysema and other chronic obstructive pulmonary disease, fracture, hypertension, pneumonia in the sequence of death causes increased. Intracranial injury ranked from the fourth in2005rising to the third in2008; bronchitis and emphysema and other chronic obstructive pulmonary disease in disease of death ranked the tenth in2005rising to the eighth; fracture rose from the eleventh in2005to the ninth in2008; hypertension rose from the sixteenth in2005to the ninth in2008; pneumonia from the twelfth2005to the tenth2008.5. From2005to2008, the ratio of the top10malignant tumor diseases of the residents of Yanbian Prefecture were54.86%,56.78%,50.84%,58.11%; the top10malignant tumors and malignant tumors were in total of82.15%,80.83%,83.85%,80.96%. In2005, the top10overall ranking in malignant tumor, liver and intrahepatic bile duct cancer ranked the first, accounting for14.81%of malignant tumor. In2006, the overall ranking of Yanbian residents of10malignant tumors, trachea, bronch us, lung cancer and liver and intrahepatic bile duct cancer and breast cancer ranked the top3, but changed slightly; trachea, bronchus, lung cancer accounted for15.69%, which ranked the first. In2007, the top10malignant tumors in Yanbian residents still had not changed, but the part of the constitution of the diseases changed greatly. Among them, bile duct malignant tumor growth of liver and intrahepatic rose from14.81%in2005to25.85%in2007. Malignant tumor of breast and female genital tumors showed decreased. In2008, the overall ranking of top10malignant tumors of Yanbian residents, trachea, bronchus, and lung cancer ranked the first. In summary, during these four years, malignant tumors in residents’disease of Yanbian Prefecture had no obvious change, showing that the10kinds of diseases are the highest incidence malignant tumor in Yanbian. Among them, the top3malignant tumors were tracheal, bronchial, lung cancer and liver and intrahepatic bile duct cancer and breast cancer.6. From2005to2008, the majority of hospitalized patients suffering from the top10malignant tumors in Yanbian Prefecture (male, female total) concentrated in the age of45to59and age group of60, accounting for89.93%. In the age group of15to44, incidence of malignant tumor is a malignant tumor of breast, female genital malignant tumors, leukemia and liver and intrahepatic bile duct cancer, accounting for28.42%,29.02%,43.40%, and10.02%respectively. Among them, the leukemia mainly concentrated in the age group of5to44, accounting for43.40%. Age group0to4and5to14suffered the main disease:leukemia. During the4years, liver and intrahepatic bile duct cancer in all age groups increased with the increase of the age (Quadratic R2=0.993, F=142.473, P<0.01); trachea, bronchus, lung malignant tumor in all age groups increased with the increase of age (Quadratic R2=0.995, F=217.669, P<0.01); gastric malignant tumor in all age groups increased with the increase of age (Quadratic R2=0.998, F=399.709, P<0.01); malignant tumor in the rectum and anal canal in all age groups increased with the increasing of age (Linear R2=0.972, F=105.824, P<0.01); malignant tumor of colon in all age group increased with the increase of age (Quadratic R2=0.924, F=36.415, P<0.01); urinary tract malignant tumor in all age groups increased with the age increase (Linear R2=0.870, F=20.137, P<0.05); esophageal neoplasm in all age groups increased with age increased (Linear R2=0.870, F=20.137, P<0.05).7. From2005to2008, the top10of the hospitalized residents of Yanbian had no change. During the four years, the rate of total cancer crude incidence fluctuates greatly in Yanbian. In2008the rate was172.89/10million. In2008the order of the top5malignant tumors is:trachea and bronchus and lung malignant tumor, liver and intrahepatic bile duct malignant tumor, malignant tumor, breast malignant tumors of female reproductive organs and malignant gastric tumor. This sequence is similar to that of2006. Liver and intrahepatic bile duct cancer ranks the first in2005and2007, but the second in2008.8. From2005to2007, the rank of male hospitalized cancer incidence of the top4diseases of the residents in Yanbian had no change and these diseases according to the incidence can be placed as following:the liver and intrahepatic bile duct malignant tumor of trachea, bronchus, lung, malignant tumor, malignant tumor of stomach, and rectum and sigmoid colon junction, rectum, anus and anal canal malignant tumor. Malignant tumor of esophagus is the seventh in2005, the eighth in2006, while in2007ranked to the fifth. On the contrary, during these three years, the sequence of the top5cancer crude incidence occurring to women were: breast cancer, the liver and intrahepatic bile duct cancer, the trachea, bronchial, lung cancer, malignant tumors of the female reproductive organs, the recto sigmoid junction, rectum, anus and anal canal malignant tumor. During the three years, the top5diseases of malignant tumor incidence did not change. We need pay attention to the rank of the malignant tumor increased from the eighth in2005to the sixth in2007, and the incidence of leukemia decreased from the sixth and seventh in the former two years to the eighth. In addition, the rate of the liver and intrahepatic bile duct cancer crude incidence rose from the fourth in2005and2006to the second in2007.9. From2005to2008, the sequence of the death cause in5malignant tumor had no change as following:①liver and intrahepatic bile duct,②the trachea, bronchial, lung,③stomach,④leukemia,⑤esophagus.. In addition to the rate of gastric cancer crude incidence increased year by year, other hospital mortality has declined. In addition, the sequence of death cause of malignant tumor breast ranked the eighth in2005and2006increasing to the sixth in2007and2008.Conclusions:1. From2005to2008, the malignant tumors were the second cause of mortality and the top5malignant diseases and mortality had no change followed by the liver and intrahepatic bile duct cancer, tracheal and bronchial and lung cancer, gastric cancer, leukemia, malignant tumor of esophagus. Among them, the liver and intrahepatic bile duct cancer ranks the first.2. From2005to2008, the male mainly suffered from the liver, intrahepatic bile duct malignant tumor and trachea, bronchus, lung malignant tumor while the female mainly got malignant tumor of breast and liver and intrahepatic bile duct cancer.3. From2005to2008, the top10malignant tumors had no change. The most common malignant tumors in Yanbian are tracheal and bronchial and pulmonary malignant tumor, liver and intrahepatic bile duct cancer, breast cancer, malignant tumors of female genital organs and gastric malignant tumor, which should be the focus of prevention and treatment of malignant diseases.4. From2005to2008, patients with malignant tumor mostly concentrated in the age from45to59and age group of60. Malignant tumors of female reproductive organs of leukemia, malignant tumor, malignant tumor of breast were mainly occurred in the age group15to44. The age group0to4and5to14suffered the main disease:leukemia. During the four years, the age composition ratio increased in the liver and intrahepatic bile duct cancer, tracheal and bronchial and lung cancer, gastric cancer, malignant tumor, colon, rectum and anal canal malignant tumor of urinary tract malignant tumor, malignant tumor of esophagus with the increase of age. |
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