| Objective: Meta-analysis comparison of the efficacy of plate fixation andintramedullary nailing in the treatment of adult humeral shaft fractures. Methods:Computer search Pubmed (1990-2012April), OVID medical journal database(1990-2012April), MEDLINE (1990-2012April), the CNKI (1990-2012April) and theChinese Biomedical literature Database(1990-2012April)randomized controlled trialpaper plate fixation and intramedullary nailing in the treatment of adults with humeralshaft fracture, and to evaluate the methodological quality of included studies. Statisticalsoftware using the RevMan5.01provided by the Cochrane Collaboration. Results: Thetrials which Jadad scale score were equal to or greater than the3points were included inarticle to8, which were a total of509patients(271cases of patients with plate fixation;intramedullary nailing in patients with238cases). Meta-analysis results show that theplate fixation group and the intramedullary nailing group treatment of adults with humeralshaft fracture with postoperative infection rate, the difference was significant [OR=2.78,95%CI,(1.04,7.40), P=0.04], the rate of postoperative complications, reoperationrate and the limited mobility of the shoulder and elbow rate lower than the intramedullarynailing group (P≤0.05) in the nonunion rate, the rate of radial nerve injury, postoperativepain, the comparison between the two was no difference significant (P>0.05). Conclusion:Plate fixation group compared with intramedullary nailing group treatment of adults withhumeral shaft fracture with postoperative infection rate, the rate of postoperativecomplications, reoperation rate and limited activities of the shoulder and elbow low, therest showed no significant difference. |