The Research On The Change Of Ambulatory Blood Pressure Before And After Percutaneous Coronary Interention

Objective:To observe the change of ABP in patients with Hypertension (HT) andCoronary Heart Disease (CHD) before and after Percutaneous Coronary Intervention(PCI),and compared with the control group who do not undergo PCI and healthypeople in outpatient service medical and to evaluate the effect of PCI on ABP of HTwith CHD.Methods: These cases which chosen from October2011to October2012in thefirst affiliated hospital, henan university of science and technology were all HT andCHD.126patients who undergo Coronary Artery Angiography (CAG) confirmed atleast one branch of coronary artery stenosis was more than70%and with completenessrevascularization were involved in the research. Among the patients96were males,and30were females. Their average age was61.18±12.15years old.106patients of HTand CHD who undergo CAG confirmed CHD but because of all sorts of reasons do notundergo PCI. Among the patients82were males, and24were females. Their averageage was60.82±11.45years old. In addition chosen98cases of healthy people inoutpatient medical from the same hospital in the same period as control group. Amongthis group74were males, and24were females. Their average age was59.32±11.06years old. Recorded the patient’s clinical information detailedly. Statistical analysissoftware SPSS17.0was used to analyze ABP and HRV in different groups, and toevaluate the effect of PCI on ABP of HT with CHD.Results:1. PCI group and medicine group were compared with control group:There was a significant difference (P<0.01) in ABP and HRV before treatment indifferent groups, the parameters of ABP and HRV improved obviously..2. PCI group: ABP and HRV were made before PCI and one week, one monthrespectively after PCI. Comparison of ABP and HRV within the PCI group: There wasno significant difference in ABP and HRV after a week of PCI(P>0.05), after one month of PCI, the parameters of ABP and HRV improved obviously,there was asignificant difference(P<0.01).3. ABP and HRV were made before treatment and one week,one monthrespectively after treatment in patients with HT and CHD who undergo regularmedicine treatment. Comparison of ABP and HRV within the medicine group:Therewas no significant difference in ABP and HRV after a week of treatment (P>0.05),after one month of treatment, the parameters of ABP and HRV improved to someextent, there was a significant difference(P<0.05).4. Comparison of ABP and HRV between the PCI group and the medicine group:There was no significant difference in ABP and HRV before treatment and after a weekof treatment (P>0.05), the parameters of ABP and HRV in two groups at the samelevel.After one month of treatment, the parameters of ABP and HRV improvedobviously in two groups,there was a significant difference(P<0.05).Conclusion:1.The main change of ABP in patients with HT and CHD:The mean bloodpressure and pulse pressure and blood pressure variation and blood pressure loadincreased obviously, blood pressure circadian rhythm disappeared.2. Successful PCIcan markedly improve the autonomic nervous function as well as the parameters ofABP of HT with CHD and make blood pressure is easy to control.3. To some extentregular medicine treatment can improve the autonomic nervous function as well as theparameters of ABP of HT with CHD. PCI is more obvious and stable on the influenceof ABP than the medicine treatment and it is better on the control of blood pressurethan the medicine treatment.