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Effectiveness Of5-aminolevulinic Acid With Photodynamic Therapy In Treatment Of Condyloma Acuminatum

Posted on:2014-04-08Degree:MasterType:Thesis
Country:ChinaCandidate:Z W A l w i W i j a y a HuanFull Text:PDF
GTID:2254330422962692Subject:Dermatology and Venereology
Abstract/Summary:PDF Full Text Request
Objective: To assess the efficacy and safety of5-aminolevulinic acid(ALA) with Photodynamic Therapy (PDT) for the treatment of multipleCondyloma Acuminatum (CA).60patients with multiple CA wereobserved before and after the treatment.Methods: A20%5-ALA solution was applied to the CA area3hoursbefore illumination with red light (635nm,100mW/cm2,80J/cm2). Thetreatment was repeated14days after the first treatment if the lesions werenot completely resolved.Results: The complete response rate, recurrence rate and adverse effectin the group were analyzed. After3to4treatments, the completeresponse rate is86.67%(52out of60patients) and recurrence rate is15%(8out of60patients). Adverse effects reported including pain or stingingsensation during and prior to24hours after the illumination.
Keywords/Search Tags:Condyloma Acuminatum, 5-Aminolevulinic acid, Photodynamic Therapy
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