| Objective: To investigate the clinical characterization ofnoncompaction of ventricular myocardium (NVM) in children.Method: A retrospective study of20patients hospitalized fromSeptember2007to November2012was performed in Chongqing MedicalUniversity affiliated children’s hospital. This retrospective analysis wascarried out according to medical history of patients, clinical manifestation,auxiliary examinations, treatment processes and follow-up results.Result：In20NVM patients,16patients showed varying degree ofheart failure, which accounted for80%of total NVM patients，10(50%)with an arrhythmia, there were no children with thrombosis or embolicevents during this time. Chest x-ray showed an enlarged heart in12patients(60%),abnormal ECG was showed in10patients(50%).Typicalchanges of NVM were seen in all patients in UCG.All the20patients hadan active medical treatment and5patients were dead of the aggravation ofheart failure. During the follow-up of8patients for7.86months, thesymptoms were greatly controlled, elevated EF can be seen by UCG after treatment and had statistic significance(P＜0.05);Left VentricularShortening Fraction(FS) were increased, left ventricular diastolicdiameter(LVD)、 right ventricular diameter(RVD) and ratio ofnoncompacted to compacted myocardial layers(NC/C) were decreasedafter treatment but had no statistic difference(P＞0.05).Conclusion：Different degree of heart failure is the chief complaint ofNVM patients; the main auxiliary examination for the diagnosis of NVM iscolor doppler electrocardiography. With active internal medicine treatment,clinical symptoms and left ventricular dysfunction can greatly improved inshort-term, but the long-term follow-up promised a poor prognosis. |
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