The Clinical Research Of Strengthening The Spleen Counseling The Liver Detoxing Formula Combined With MDCF Chemotherapy In The Treatment Of Advanced Gastric Cancer

Objectives:Through literature review, system of gastric cancer etiology and pathogenesis, syndrome differentiation and treatment of TCM, invigorating spleen and soothing liver detoxification treatment of gastric cancer and theoretical basis, through the observation of invigorating spleen and soothing liver detoxification decoction combined with chemotherapy on patients with advanced gastric cancer lesions size, quality of life, physical condition, TCM syndromes, the changes of tumor marker, chemotherapy toxicity reaction, comprehensive evaluation of the clinical efficacy and safety, and provide clinical data for the development of traditional Chinese medicine treatment of gastric cancer.Methods:Take the computer randomized controlled clinical trial design,40patients with advanced gastric cancer patients were randomly divided into2groups,20cases of which treatment group (strengthening the spleen counseling the liver detoxing formula+modified DCF regimen therapy), the control group (simple improvementDCF regimen) in20cases. DCF chemotherapy,21days for a treatment process, observe the two courses. The treatment group oral medicine in chemotherapy began the first day,1day. Objective tumor efficacy, tumor markers, TCM efficacy, quality of life observation, safety assessment index were recorded before and after treatment,and using statistical software for statistical analysis.Result:Study on comparison of the two groups were observed before and after the TCM syndromes, physical condition and quality of life, P<0.05, the difference was statistically significant, suggesting Jianpi Shugan Jiedu Decoction can improve patients above three aspects; and in the objective effect, tumor index and safety index, comparing the two groups, P>0.05, no statistically significant difference, indicate three aspects of invigorating spleen and soothing liver detoxification hereby and can not gain advantage.Conclusion:Strengthening the spleen counseling the liver detoxing formula can improve the adverse reaction of chemotherapy in gastric cancer patients, is better than that of chemotherapy alone in improving the quality of life of the patients and improve physical condition, in the objective results, indicators of tumor markers and safety compared with chemotherapy alone had no obvious advantage.