| Objective: The combined appllication of1eft atrial volume trackingmethod(LAVT),quantitative tissue velocity imaging (QTVI) and Color M-mode to evaluate thechanges of left ventricular structure and function in patients with hypertension atrialfibrillation (HAF)and lone atrial fibrillation(LAF).Methods: Fifty persistents with atrial fibrillation divided into Lone atrialfibrillation group(n=24) and hypertension atrial fibrillation group(n=26).Twenty-fivenormal volunteers served as control group.Parameters derived from routine2Dultrasound,color M-mode and QTVI were acquired in the two groups and comparedwith the normal group.Left ventricular ejection fraction(LVEF) were calculated byTeich.Echocardiographic evaluations included LA diameter(LAD1),LA majordimension (LAD2),LA minor dimension (LAD3),RA major dimension (RAD1),RAminor dimension (RAD2).LA maximal area (LAAmax),LA maximalvolume(LAVmax),LA minimal volume(LAVmin),systolic LA filling rate(dv/dtS) anddiastolic LA emptying rate(dv/dtE) were derived using LAVT.Then calculated the LAemptying fraction(LAEF).Results:1.Commonly data:The age,sex, LVEDD,LVESD,IVSTd, LVPWT andLVEF were not significantly different(P>0.05). The heart rate in in atrial fibrillationgroup is faster (P<0.05)2.Left ventricular function: Compared with the values in controlgroup,the E,E/Ve were significantly ascend and the Vp,Vs,Ve were descend in atrialfibrillation group(all P<0.05);The E/Ve were significantly higher and the Vp,Vs,Vewere lower in hypertension atrial fibrillation group compared with Lone atrialfibrillation group (all P<0.05).There were no differences in E between hypertensionatrial fibrillation group and Lone atrial fibrillation group(all P>0.05).3.left atrialstructure and function:Compared with the values in control group,the LAD1,LAD2, LAD3,RAD1,RAD2,LAAmax,LAVmax,LAVmin and dv/dtE were significantlyascend and the LAEF,dv/dtS were descend significantly in atrial fibrillation group(allP<0.05); The LAAmax,LAVmax,LAVmin were significantly higher and the LAEF,dv/dtS,dv/dtE were lower in hypertension atrial fibrillation group compared with Loneatrial fibrillation group (all P<0.05).There were no differences in left and right atrialdiameter between hypertension atrial fibrillation group and Lone atrial fibrillationgroup(all P>0.05).Conclusion: There are more obvious changes of left atrial structure than leftventricuar structure in atrial fibrillation group. Left ventricuar dysfunction exists inatrial fibrillation group and the left ventricular function in patients with HAF weresignificantly impaired; Parameters derived from LAVT,QTVI and color M-mode canquantify the LV and LA function in AF patients sensitively and accurately. |