The Limb-salvage Treatment Of Limb Malignant Tumors A Clinical Outcome Study

Objective: To explore the clinical efficacy of limb malignant tumor withlimb-salvage treatment.Methods：From May2006to May2012，63patients suffering from malignantbone tumors were treated with artificial prosthesis replacement or reconstruction ofthe defect with recycled pasteurized autograft in our hospital were entered in the study.Adopting questionnaire investigating way to collect the data of evaluating curativeeffect by telephone, letter and out-patient callback. We analyzed the situation offollow-up after treatment, the3-year survival rate、operative complications、life qualityimproving、pain relieving and physical function.Results:1.Karnofsky Performance Scale（KPS） of patients were significantlyincreasd after limb-salvage operation between two groups over six months(P<0.05),which indicated a dramatically improved quality of life.2In two gruops, there was statistical difference between the pre-operative andpost-operative of the Enneking system (P<0.05). The rate of excellent and good limbwas76%and70.6%respectively.3.There was no statistical difference between the rates of local recurrences andcomplications represented after operation (P>0.05). The rate of limb salvage was92%and82.4%respectively within two groups.4.Long term prognosis of limb-salvage operation has no improvement,namely noobvious raise in survival rate.Conclution:(1) The prognosic of limb malignant tumor with limb-salvagetreatment won’t chang,however postoperative limb performance and quality of lifewere significantly improved.(2) Artificial prosthesis replacement or pasteurized autograft showed no remarkable difference in postoperative metastasis and recurrence,while prosthetisreplacement suggested a marked reduction in postoperative complications and betterlimb performance.