Clinical Observation Of Narcotrend Monitor Used In The Depth Of Anesthesia In Elderly Patients With General Anesthesia

Objective: This study was designed to investigate the impact of Narcotrendmonitor in elderly patients with general anesthesiaMethods: Sixty patients who received total intravenous anesthesia(ASAII-III,60~75years old) that were scheduled to receive stomach colorectalsurgery were randomly divided into3groups: standard practice(control group,n=20),lighter anesthesia group (group NL,n=20), deeper anesthesia group (groupND,n=20).They were divided at random with a number list.Group NL was assigned toexpect Narcotrend index of37~64, Narcotrend stage:D0-D2; Group ND was assignedto expect Narcotrend index of13~36, Narcotrend stage:E0-E2.Record general situationof patients,such as gender,age,educational level, duration of surgery; propofol andremifentanil consumption and the end of operation over to the time of awarenessrecovery(t1),tracheal extubation(t2),directional force to restore (t3) were recorded;theMAP,HR were observed at the time points of before induction(T1),beforeintubation(T2),intubation moment(T3), at the beginning of the operation (T4), at theend of the surgery(T5), awareness recovery(T6),tracheal extubation(T7),directionalforce to restore(T8),and the NTI and NTS at T6,T7,T8; using MMSE to evaluatepostoperative cognitive function at the time of the day before surgery and24h aftersurgery,and use modified Brice interview questionnaire to survey patients with andwithout intraoperative awareness.Results: The general situation of the patients in three groups have no significantdifference（P＞0.05）. Group NL and group ND needed significantly less propofolthan group C,and t1,t2,t3are more shorter. The indicators of group ND have astatistically significant differences compared with group NL.Comparison doses ofremifentanil there was on significant difference（P＞0.05）. MAP of three groups of patients in T1, T2, T3, T4, T5, T6, T7, T8had no statistical significance（P＞0.05），group C and group ND compared with NL group, the difference of HR wasstatistically significant in the points of T3，T4，T5.In T6,T7,T8,comparison betweengroup NL and group ND,there was no significant difference of NTI. In awakeningperiod, patients in group NL ang group ND with different level of NTS cases tocompare the difference have no sense of statistics.There was no intraoperativeawareness happens to both patients. POCD occurred in0patients who receivedstandard practice and deeper anesthesia，and1patients (5%) who received lighteranesthesia on24h after surgery.Conclusion: Narcotrend monitor can facilitate a significant reduction ofrecovery times and propofol consumption, improve the recovery and restorationquality in elderly patients with general anesthesia.