| Objective：Iodine Deficiency Disorders (IDD) refers to embryonic development to adulthooddue to the intake of iodine deficiency disorders caused by a series of general term,including endemic goiter, cretinism and so on. Serious threat to human health, diseaseseriously affecting the quality of population. Our country is a serious threat to nationaliodine deficiency disorders by. After years of efforts, China has basically achieved theelimination of IDD. However, to ensure sustainable elimination of IDD is a long-termstrategic goals. This study of2008to2012in Jilin Province availability of iodized saltand urinary iodine and thyroid volume of children, women of childbearing age iodinecontent in urine investigation, prevention and treatment of disease status of iodinedeficiency in Jilin Province, and in the meantime put forward countermeasuresrecommendations.Methods：Using cluster random sampling method, the iodine content of edible salt in Jilinarea under the jurisdiction of nine counties,8-10year-old children iodized salt, theiodine content in urine and thyroid volume, urinary iodine content of a sample ofwomen of childbearing age investigation. Collecting salt, according to according toGB/T13025.7-1999direct titration (Sichuan salt and other salt using enhancedArbitration Act) determination of iodine content of salt. Calculation of iodized salt,iodized pass rate, the rate of qualified iodized salt, non-iodized salt usage; childhoodthyroid checked by the diagnostic criteria of endemic goiter (WS276-2007)performed using the B-method examination. Using arsenic cerium catalyticspectrophotometry (WS/T107-2006). Urinary iodine content of children and womenof childbearing age.Using SPSS17.0statistical analysis of survey data. Experimental data to themedian (M), said rank sum test and the chi-square test was used for statistical analysis,significant test level is α=0.05. But by2012, the iodine content of salt in JilinProvince was still significantly decreased (P <0.05).Results1Jilin qualified iodine content of salt case Jilin Province from2008to2011, qualified iodized rate above99%, reaching thenational requirements, but the presence of high salt, low salt and non-iodized salt. In2012, the passing rate of iodized salt decreased rapidly, mainly in2012, after theintroduction of new standards, according to the original standard production of iodizedsalt is still for sale, thus leading to a rapid increase in the proportion of high salt, up23.8percent. But by2012, the iodine content of salt in Jilin Province was stillsignificantly decreased (P <0.05).Iodine content of salt each year of the province’s municipalities were significantlydifferent (P <0.05).2008iodine content of salt up to Tonghua City (32.99mg/kg),2009years Jilin (33.14mg/kg),2010years Yanbian (33.45mg/kg),2011years TonghuaCity (31.00mg/kg),2012up to the Yanbian region (30.64).2012Changchun, Jilin, Siping, Liaoyuan City, Hakusan City, Tonghua City,White City, Songyuan City, Yanbian qualified iodine consumption rate decreased to83.6%,72.6%,84.59%,77.4%,70.8%,84.6%,85.7%,81.06%and63.00%. Its medianiodine content of edible salt were28.08mg/kg,30.03mg/kg,28.0mg/kg,29.96mg/kg,30.27mg/kg,30.52mg/kg,26.24mg/kg,29.00mg/kg and30.64mg/kg, weresignificantly lower than the previous four years the median iodine content of salt (P<0.05). Within five years of non-iodized salt is not monitored for the Liaoyuan city,Hakusan, Tonghua, Baicheng;2008to monitor the non-iodized salt city of Changchun,Jilin, Siping, Yanbian;2009to monitor the non-iodized salt city of Songyuan; In2010the province were not monitored non-iodized salt;2011and2012to monitor thenon-iodized salt city of Siping, Songyuan, Yanbian.2Children aged8-10Jilin monitoring results of iodine deficiency disordersChildren aged8-10Jilin ingestion were higher proportion of qualified iodized salt,96.3%(Jilin)-98.0%(Yanbian). Parts to7parts of high salt, low salt,35parts parts.More than90%within the normal range, but at the same age, thyroid volumemunicipalities have significant differences in thyroid volume in children (P <0.05),8-year-old group, the largest Hakusan thyroid volume (median2.99ml),9thyroidvolume largest age group is white City (median2.88ml),10-year-old group is thelargest of Siping City (median3.32ml);8-year-old group of children are increasingthyroid volume in Changchun City, Jilin, Siping City and White City, the presence ofchildren9years old increased thyroid volume in addition to Changchun, SongyuanCity, other cities were present,10years old in addition to the group of Changchun City, Jilin and Yanbian, other cities have increased thyroid volume of children. However,the proportion of the municipalities in which they appear no significant difference (P>0.05).Children urinary iodine content50μg/L ratio of5.89%on average, to eliminateiodine deficiency disorders standards. Each city had urinary iodine levels below thechild50μg/L, where the proportion of Siping, Liaoyuan, Tonghua, Matsubara ishigher than10%.8-year-old group and its median urinary iodine <100μg/L,100-200μg/L,>200μg proportion/L had no significant difference (P>0.05);9-year-old group medianurinary iodine levels were significantly different (P <0.05), the lowest Hakusan(149.6μg/L), urinary iodine content <100μg/L, the highest proportion of children toSiping City (27.3%), urinary iodine levels>200μg/L, the highest proportion ofchildren white City (71.4%) as;10-year-old group median urinary iodine levelssignificantly different (P <0.05), the lowest in Liaoyuan City (99.5μg/L), urinaryiodine content <100μg/L for children but also for the highest proportion of LiaoyuanCity (54.5%) urinary iodine content of100-200μg/L,> no significant difference (P>0.05) the proportion of children200μg/L.3Women of childbearing age urinary iodine findingsCities in Jilin Province median urinary iodine women of childbearing age weresignificantly different (P <0.05), the lowest median urinary iodine content is Yanbian(130.75μg/L), the highest Hakusan (268.32μg/L). Urinary iodine levels <100μgproportion/L of municipalities have significant differences (P <0.05), the highestYanbian (43.3%) and the lowest in Changchun City (10.5%); Proportion of urinaryiodine content in100-300μg/L was also significantly different (P <0.05), which is thelowest in Hakusan City (34.4%); Urinary iodine levels>300μg proportion/L ofmunicipalities have significant differences (P <0.05), which is the highest proportionof Hakusan City (44.4%).Conclusion：2008-2011Jilin iodized salt coverage rate of qualified iodized salt, urinary iodine,thyroid volume, iodine content in urine of women of childbearing age are up tostandard to eliminate iodine deficiency disorders.2012although the rate of decline ofqualified iodized salt, iodized salt coverage but still more than99%.But there are stillnon-iodized salt and low-salt, iodized salt monitoring still needs to intensify. Monitoring should be focused on children and women of childbearing age iodized saltintake and urinary iodine. |
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