Prognostic Value Of Etiology In In-Hospital Patients With Heart Failure

Objective To determinate the prognostic value of etiology in patients with heart failure (HF).Methods Patients admitted to first hospital of Lanzhou University with heart failure were investigated between January2007and December2010. All patients were followed up through telephone calls to understand whether patients were death. Patients were classified into five etiology groups:coronary heart disease, hypertension, dilated cardiomyopathy, valvular disease, multifactor group. Cox proportional hazards analyses were used to explore the differences in the mortality.Result A total of513patients with heart failure were enrolled. There were231patients (45%) have died at the end of followed up. NYHA classification of cardiac function, complication, systolic blood pressure, left ventricular ejection fraction, sodium ion, calcium ion, blood glucose, total bilirubin and blood creatinine significant effect the risk of mortality (P<0.05). In multivariable analysis, compared with valvular disease group, the HR (Harzard ratio) were2.517(95%CI,1.477to4.290, P＜0.05) and2.480(95%CI,1.375to4.474, P＜0.05) in patients with coronary heart disease and dilated cardiomyopathy, respectively(P<0.05). Conclusion Different etiologies of heart failure demonstrate different prognoses. Heart failure due to coronary heart disease and dilated cardiomyopathy carried a worse prognosis than that of valvular disease.