The Dependability In The Results Of CAG In CAD And Clinical Data To Study The Relationship Between TCM Syndrome-Type In CAD

Background: coronary angiography (CAG) is a general application of clinic, it’sthe "golden standard" to diagnose Coronary artery disease (CAD) at present. AthoughSome researches have shown there are some difference in the results of CAG, most ofthese researches only investigate some small samples or part of the type of syndrome, itcann’t reflect all of the pattern of syndrome totally in CAD, also cann’t produce activeguideline significance in the diagnosis and treatment of CAD. My research has a largesample, I observe the coronary artery pathological changes of the patients and differentpattern of syndrome of TCM(traditional Chinese medicine), furthermore with moreobjective evaluation to compare the differences in each type of syndrome with the resultof CAG. With these, I approach the modern pathobiology in different pattern of syndromeof TCM, it provide the theory basement of the choice of Chinese medicinal materials tointerfere in CAD and clinical directions.Objects: To observe the dependability in the results of CAG in CAD and clinicaldata to study the relationship between TCM syndrome -type in CAD.Methods: 866 patients who were done coronary artery angiography(CAG), includinga normal group of 205, a coronary atherosclerosis group of 229, a CAD group of432(≥50% coronary stegnosis involving the main branches of aeteria coronaria can be thediagnose of CAD). I collect their common information, clinical data and the result ofCAG to analyze these dependability, run the dialectical typing with multisyndrome -type.Results: 1、The level of angina cordis, LDL—C, the pathological extent of coronarydisease, the pathological characteristic, gensini scores and leaman scores in CAD withthe Sydrome-type of stagnant blood in heart group were significant different than those inother control group. The ACS patients of the group were also more than the non stagnantblood group. 2、The multi syndrome type deficiency of both qi-yin with phlegm andstagnant blood obstruction scores higher than any other groups. 3. The gensini scores andleaman scores had the positive correlation with the pathological extent of coronarydisease, the pathological characteristic,and CAG diagnosi s, also the negative correlationwith HDL—C, Apo (al), LVEF. Conclusions: 1. these clinical research combined the TCM Syndrome Differentiationtype with the CAG result,with a large sample to observe the relations between them. itshew the Sydrome-type of stagnant blood in heart group of CAD patients were more thanothers, and had more critical pathological changes than non- stagnant blood group,it hadshown the key palce of stagnant blood in the progression of CAD. 2. according toCoronary artery stegnosis scores, Themultiple TCM Syndrome Differentiation type ofCAD were asthenia of healthy energy with asthenia of healthy energy. 3. The gensiniscores and leaman scores had the negative correlation with HDL—C, Apo(al) alsoshown the protection of HDL—C, Apo (al) In the course of coronary artery stegnosis.