The Study Of Prognostic Factors Of Patients With Peptic Ulcer Bleeding

Objective Analyzing the risk factors of rebleeding in hospitalized patients withpeptic ulcer bleeding.Materials and Methods A retrospective study was conducted1210patients who wereadmitted to General hospital of Ningxia Medical University with peptic ulcer bleeding from2002to2011. The patients were divided into two groups:1040patients who were stable incontrol group,170patients were in rebleeding group, analyzing the clinical data of thepatients in two groups.Results1、The results of comparison between control group and rebleeding group is significantlyin age, gender, resident place, anticoagulant use, serious comorbidity, hematemesis, shock,blood transfusion, hemoglobin, albumin, urea nitrogen, the relative value of neutrophils,blood platelets, ulcer location, ulcer size and Forrest class.2、Univariate analysis showed that resident place, anticoagulant use, hematemesis, shock,blood transfusion, hemoglobin, albumin, urea nitrogen, the relative value of neutrophils,blood platelets, ulcer location, ulcer size and Forrest class are risk factors for the peptic ulcerrebleeding.3、Multivariate logistic regression analysis showed that hemoglobin (OR=7.332,P=0.004),shock(OR=5.245,P=0.000),ulcer size(OR=4.765,P=0.029), Forrest clas（sOR=7.735,P=0.000）are independent risk factors for peptic ulcer rebleeding. Four indicators to assess the role ofthe risk rebleeding: Forrest class> hemoglobin> shock> ulcer size.Conclusion Forrest class, hemoglobin,shock,ulcer size are the risk factors for peptic ulcer rebleeding. These factors have a certain value in predicting the rebleeding and guiding theclinical treatment. Objective Analyzing the risk factors of mortality in hospitalized patients with pepticulcer bleeding.Materials and Methods A retrospective study was conducted1210patients who wereadmitted to General hospital of Ningxia Medical University with peptic ulcer bleedingfrom2002to2011. Among the patients,1170cured patients were in control group,40deadpatients were in mortality group, analyzing the clinical data of the patients in two groups.Results1、The results of comparison between control group and mortality group is significantlyin age,comorbidity,shock, rebleeding, albumin, blood coagulation, Forrest class(P<0.05).Thepatients who were older than sixty-five years, admitted to hospital with shock, comorbidity,rebleeding, abnormal coagulation, Forrest class≧Ⅱb in mortality group were more higherthan control group,the albumin was lower than control group.2、Univariate analysis show that age,comorbidity,shock,rebleeding, blood coagulation arerisk factors for the mortality of peptic ulcer bleeding.3、 Multivariate logistic regression analysis show that age (OR=4.821, P=0.008),comorbidity (OR=29.959,P=0.000), rebleeding (OR=9.627, P=0.002)are independent riskfactors for the mortality of peptic ulcer bleeding. The role of the three factors in predictingthe risk of mortality: comorbidity> rebleeding> age.Conclusion Age,comorbidity,rebleeding are independent risk factors for the mortalityof peptic ulcer bleeding. The factors play a important role in predicting the mortality of hospitalized patients with peptic ulcer bleeding.