Risk Factors Analysis And Prevention Of Urethral Stricture After Transurethral Plasmakinetic Resection Of The Prostate

Objective：To investigate the risk factors and preventive measures of urethralstricture after transurethral plasmakinetic resection of the prostate (PKRP).Methods：From January2011to December2013, there are684BHP patient hadundergone the PKRP surgery in the Urology Surgical Department of the FirstAffiliated Hospital of Fujian Medical University, including225cases in2011,217cases in2012and242cases in2013. Postoperative urethral stricture occurred in15patients (urethral stricture group), with the age of59-87(71.4±7.1) yearsold. Randomly selected15cases with no urethral stricture from the years, totally45cases (non-urethral stricture group), with the age of57-88(72.9±7.2) years.We have collected60patients’ data by admitting patients to hospital see doctoragain, accessing to electronic medical records and telephone. To analyze the riskfactors of PKRP on urethral stricture, we have selected and used7index, includingthe patients age, BPH duration time, preoperative urinary tract infection, preoperativeprostate size, operation excision prostate weight, operation time, and indwellingcatheter time. All data were analyzed by SPSS17software. The measurement datawere tested by Independent sample t, and the data represented by mean±standarddeviation; count data were tested by χ2; if P<0.05, there is statistically significant;screening of the independent variables when P<0.05, and bring into the Logisticregression model to make the multivariate analysis.Results: There is no correlation between the PKRP on urethral stricture whenP>0.05of those five factors, the patients age, BPH duration time, preoperativeprostate size, operation excision prostate weight, and operation time. While there iscorrelation when P<0.05of these two factors, preoperative urinary tract infection, andindwelling catheter time. The further Logistic multivariate analysis showed that thepreoperative urinary tract infection and indwelling catheter time were independentrisk factors of urethral stricture after PKRP (P<0.05), the OR values were8.050and 1.607.Conclusion: The preoperative urinary tract infection and indwelling cathetertime were independent risk factors of urethral stricture after PKRP. Thus there aremany effective control measures of urethral stricture after PKRP, such as activelycontrol of preoperative and postoperative urinary tract infection, avoid operationinjury, indwelling catheter should not be too thick and catheter indwelling time shouldnot be too long. The key of healing urethral stricture after PKRP is to strengthen thefollow-up of patients after PKRP, accomplish early discovery, early treatment, andchoose appropriate treatment methods according to the narrow site, length, degree andso on.