Investigation Of The Prevalenceand And Related Factors Of Cholelithiasis In Wrinkly Of Xinzhou Voluntary Examination Population

Objective:Investigate the prevalence and the related factors of cholelithiasis in the wrinkly of Xinzhou voluntary health examination population, clear the prevalence and risk factors of cholelithiasis in the wrinkly of Xinzhou voluntary health examination population, and to provide scientific basis for the prevention and treatment of the wrinkly cholelithiasis.Method:l.The objects of investigate were the crowd of2226people aged45-59years health examination in health examination ceter of Xinzhou and Weikang health examination ceter in2013.2.The content of investigation include age.gender.height. blood pressure,blood glucose, blood lipids other biochemical indicators of inspection, and ultrasonography of the liver andbiliary system.3.The main indicators of investigation include the prevalence of cholelithiasis and related diseases in this population, such as hypertension, hyperglycemia, diabetes, hyperlipidemia, fatty liver, and characteristics and related factors of cholelithiasis in the population.4. Statistical analysis of the all data by using SPSS for windows17.0statistical software. The prevalence rate of disease expressed as a percentage and usesX2Test to analysis. The measurement data expressed as the mean value±standard deviation (x±s)and analyzed by t-test. The risk factors were analyzed by univariate analysis. The inspection level of test a=0.05, p <0.01is considered the significant difference, p<0.05is considered difference.Result:l.The number of cholelithiasis, hypertension, fatty liver, hyperglycemia, diabetes and Hyperlipidemia, were respectively177,852,717,237,153and1233in the wrinkly population of Xinzhou, the prevalence rates were8.0%,38.6%,32.2%,10.6%,6.9%and55.3%correspondingly.2.The total prevalence rate of cholelithiasis was12.5%in the wrinkly population, male5.7%, female10.0%, the prevalence rate of cholelithiasis in females significantly higher than males(p<0.01).The prevalence rate of cholelithiasis of women was significantly higher than men in each age group (p<0.01). The prevalence rate of cholelithiasis in female have shown an increase trend with the age increasing (p<0.05), the prevalence rate of cholelithiasis of male of age50-54was lower than males of age45-49and55-99(p>0.05).3.The prevalence rate of cholelithiasis in hyperlipidemia and hypercholesterolemia population was significantly higher than normal lipid population(p<0.05), the prevalence rate of cholelithiasis in mixed hyperlipidemia and hypertriglyceride population compared with norma llipid groups was no difference (p>0.05);The prevalence rate of cholelithiasis in the diabetic and hyperglycemic population were significantly higher than the normal blood glucose population (p<0.01, p<0.05); The prevalence of cholelithiasis in fatty liver population was significantly higher than non-fatty liver population (p<0.01); The prevalence of cholelithiasis in hyoertension population was significantly higher than non-hyoertension normal blood pressure population (p<0.01).6. Univariate analysis showed, the age, SBP(Systolic blood pressure), DBP(Diastolic blood pressure), TC (Total cholesterol), F PG (Fasting plasma glucose) in the cholelithiasis group were significantly higher than the non-cholelithiasis group (P<0.05), BMI(body mass index) and TG (Triglyceride) were no difference from the non-cholelithiasis group (P>0.05), The prevalence rates of high blood glucose, diabetic, hyperlipidemia, fatty liver, hypertension were significantly higher than the non-cholelithiasisgroup (P<0.05). The dichotomous Logistic regression analysis showed, the six indicators of gender, age, hypertension, diabetes, hyperlipidemia, fatty liver and high-density lipoprotein were closely related to cholelithiasis.