Research On The Effects Of Tonifying Spleen And Kidney Therapy To Chronic Immune Thrombocytopenic Purpura Of Spleen And Kidney Deficiency Syndrome

BackgroundImmune thrombocytopenic purpura (Immune thrombocytopenic purpura, ITP) is due to immune dysfunction caused by antibodies produced by the body’s own platelets (Platelet autoantibodies) and binds to the platelet surface leads to platelet monocyte-macrophage system was engulfed disease, clinical characterized mainly as thrombocytopenia and mucocutaneous bleeding. Chronic immune thrombocytopenic purpura (Chronic Immune thrombocytopenic purpura, CITP) refers thrombocytopenia lasting more than12months of immune thrombocytopenic purpura (ITP) patients. Chronic immune thrombocytopenic purpura (CITP) in patients with recurrent bleeding, prolonged healing, Hao Shang Yin, after a long illness, sex fluid, sinister and yang, yin and yang imaginary; chronic illness repeated bleeding Haoshang upright, with the blood off the gas, blood deficiency. The spleen is the source of qi and blood, yin and yang of the kidney is,one of chronic immune thrombocytopenic purpura and chronic illness will damage the spleen and kidney. Spleen deficiency can be both chronic immune thrombocytopenic purpura pathogenesis, can also be the cause of cause of chronic immune thrombocytopenic purpura onset occurs Nvxue, vomiting, blood in the stool, purpura and other hemorrhagic conditions, often because the patient spleen deficiency fall into "the more bleeding, more imaginary; more virtual, more bleeding," the vicious circle, the condition gradually worsened. So we used in the clinical treatment of spleen and kidney, spleen and kidney deficiency type of chronic immune thrombocytopenic purpura, to break the vicious cycle, to obtain satisfactory results. Purpose The purpose of the test is to reduce sexual purpurapatients by platelet chronic immune using the method of invigorating the spleen and kidney in treatment of spleen and kidney deficiency type, compared to clinical symptomsbefore and after treatment in patients with (and symptom score), platelet count and prednisone dosage (pine group and prednisone group of spleen and kidney strengtheningspleen); comparison of platelet in patients with autoimmunekidney method for the treatment of spleen and kidney deficiency type purpura (CITP) effect; the method of invigorating the spleen and kidney in clinical practice of platelet in patients with immune treatment of spleen and kidney deficiency type purpura (CITP) is feasible, for the promotion of platelet in patients with autoimmuneapplication method of invigorating the spleen and kidney in treatment of spleen and kidney deficiency type in clinic for idiopathic thrombocytopenic purpura (CITP) reference.Patients and MethodsFrom2012July to2013November in the outpatient department of Hematology, our hospital patients, diagnosed as chronic immune thrombocytopenic purpura(Chronic Immune thrombocytopenic purpura, CITP) andsyndrome of spleen and kidney deficiency type45patients.45patients were included in the study of clinical symptomsbefore treatment and12weeks after the changes were collected and the integral, platelet count (PLT) and prednisone dosage data. Then the data entry EXCELL, using the statistical software SPSS17, the average value of the mean+standard deviation said, with t measurement index test, with X2count index, a0.01, P<0.01was significant difference, P>0.01as no significant difference Results1, after treatment of platelet in patients with immune spleen and kidney deficiency type purpura (CITP) patients symptoms improved significantly, symptom scoresdecreased, there was significant difference (P<0.01).2, after treatment of platelet in patients with immune spleen and kidney deficiency type purpura (CITP) and platelet count (PLT) were significantly increased, with significant difference (P<0.01).3, after12weeks of treatment, according to the standard of curative effect: Jianpi Bushen group complete response(CR) in3cases, reaction (R) in10cases, invalid (NR) in2cases, the total response rate86.7%,7cases of spleen and kidney reinforcing loose groups of CR, R7cases, NR1cases ineffective, the total reaction rate93.3%, prednisone group complete response in2patients with CR,9patients with R, NR is invalid in4cases, the totalresponse rate was73.3%.4, after12weeks of treatment, according to clinical symptoms:Jianpi Bushen group cured1cases, effective in7cases, effective5cases invalid2cases, the total efficiency of86.7%, pine group clinical spleen and kidneyto cure2cases, markedly effective in8cases, effective3cases, invalid2cases, the total efficiency of86.7%clinical prednisone group,1cases were cured,2cases markedly effective, effective8cases, invalid4cases, the total efficiency of73.3%.5, the dosage of prednisone, spleen and kidney to strengthen loose group and prednisone for12weeksbehind the pine dosage were significantly reduced(P<0.01), pine group of spleen and kidney to strengthenthe reduction was more significant than prednisone dosage(P<0.01).Conclusion1, strengthening spleen and tonifying kidney can makeplatelet chronic immune spleen and kidney deficiency typedecreasing purpura patients relieve symptoms.2, strengthening spleen and tonifying kidney can makeplatelet chronic immune spleen and kidney deficiency type of thrombocytopenia purpura (PLT) patients with the number increasing3, method of invigorating the spleen and kidney in treatment of spleen and kidney deficiency type decreasing pine group purpura curative effect and strengthen the spleen and kidney is.similar, butbetter than prednisone group, and can significantly reduce the dosage of prednisone.