The Factors And Perinatal Outcome Of292Cases Of Gestational Hypertension Disease

Objective: To make clear the cause of the gestational hypertension disease, tostudy the related factors of the disease, to observe the impat of different ways ofdelivery opportunity and to provide the clinical basis for the prevention and treatment ofthe disease.Methods: Using large sample epidemiological methods of retrospective analysis,From January2012to December2013,292patients were diagnosed with gestationalhypertension disease who give birth to their childen in the Obstetrics and GynecologyDepartment of General Hospital of Beijing Military as the observation group, choseother292normal pregnant women who were randomly selected at the same time in thehospital during the same period as the control group.Collect the related parameters inthe two groups of pregnant women:1、The general situation: maternal age, gestationalage, pregnancy, childbirth time, production time, fetal sex, family history of high bloodpressure, etc.;2、Pregnancy complications, such as retinopathy, gestational diabetes,acute lung injury (ALI) and acute renal insufficiency，placental abruption and placentaprevia, heart disease during pregnancy, cerebrovascular accident, HELLP syndrome,etc.;3、Delivery end: birth gestational age, delivery methods, postpartum hemorrhage,postpartum anemia, etc.; Ending in April and perinatals: low birth weight, fetal distress,neonatal asphyxia and perinatal death. Using independent sample t test and chi-squaretest associated with gestational hypertension disease risk factors, and the disease impacton outcome in pregnancy outcomes and perinatals. Results: The risk factors associated with gestational hypertension disease:(1)With an average age of the observation group and control group in pregnant women isrespectively (30.56-4.35) and (25.0+3.13) years, the former significantly is greaterthan the latter (P <0.05); Two groups of pregnant women older than35years were15.41%and3.42%respectively, the proportion of the differences are statisticallysignificant (P <0.05);(2) The observation group and control group in pregnant womenpregnant body-mass index are respectively (27.31±1.89) and (23.45±2.11), comparedtwo groups, the former was significantly greater than the latter (P <0.05);(3) Theobservation group and control group in pregnant women with a family history of highblood pressure ratio were26.03%and5.82%respectively, compared two groups, theformer is significantly higher than the latter (P <0.05);(4) The observation group ofpregnant women retinopathy in the perinatal period, gestational diabetes, acute lunginjury (ALI) and acute renal insufficiency, the incidence of placental abruption andplacenta previa were10.62%,7.19%,4.11%,7.19%,2.74%and2.05%, control groupof pregnant women incidence of these lesions in the perinatal period are0, comparingthe two groups, the difference had statistical significance (P <0.05).2、The influence ofgestational hypertension disease in the new born: observation group of pregnant women,full-term premature production, cesarean section and vaginal delivery, the incidence ofpostpartum hemorrhage, postpartum anemia were42.81%,57.19%,90.41%,57.19%,6.85%and16.44%, control group of pregnant women the incidence were14.04%,85.96%,43.49%,85.96%,0.34%and5.14%. Comparison of similar between the twogroups have statistical significance (P <0.05).3、The ending in gestational hypertensiondisease of perinatals: the influence of the observation group of low birth weightnewborn, fetal distress, neonatal asphyxia and perinatal death rates were10.96%,5.14%,5.82%and10.96%respectively, and the control group of pregnant women the incidencewas2.74%,1.37%,1.03%and2.74%respectively, comparing the two groups, thedifference had statistical significance (P <0.05). Conclusions:1、Age(more than35years of age) may be a risk factor of gestational hypertensiondisease.2、Obesity in pregnancy may be a risk factor of gestational hypertension disease.3、family history of high blood pressure may be a risk factor of gestationalhypertension disease.4、Some pregnancy complications and perinatal complications may interact as bothcause and effect and compound the pathological process of each other.5、Gestational hypertension disease can lead to adverse birth outcomes and adverseperinatal outcome,the mastery of its delivery time and mode can be conducive toimproving the prognosis of the perinatal.