Clinical Observation Of Gastrointestinal Symptoms And Quality Of Life After Laparoscopic Cholecystectomy In52Cases

Background: Laparoscopic cholecystectomy has now replaced opencholecystectomy as the first-choice of treatment for cholecystitis. But recently, there issuggestive evidence criticized LC as an overused procedure. Moreover, increasingevdience indicated that postcholecystectomy syndrome (PCS) significantly decrease thescore of health-related QOL(HRQOL). This study investigated the effectiveness of LCon reduction in gastrointestinal (GI) symptoms in patients and the impact on quality oflife (QOL).Methods: All patients who had undergone LC performed between November andDecember2012by any one of two senior surgeons (KJ Li, G Tan) practicing at FirstAffiliated Hospital of Dalian Medical University were eligible for the study.52subjectscompleted both surveys (a GI symptom survey and quality of life survey) were included.The GI symptom survey(GISS) consists of16gastrointestinal complaints. The GISSwas developed to quantify the severity, magnitude and distressfulness of16GIsymptoms. Surveys were scored and evaluated using paired t tests.Results: Fifty-two patients were included in the final analysis. The GISS surveyindicated significant improvement in gastrointestinal symptoms was seen aftercholecystectomy but no irritable bowel symptoms or bile regurgitational gastritis (BRG)after LC (P>0.05). Significant improvement was seen in QOL (P<0.05). Conclusion:1. This study shows significant reduction in GI symptoms after elective LC.2. This study shows supports the utility of LC by marked improvement in patients’general QOL.3. Patients who suffer from bile regurgitational gastritis or irritable bowel symptomscan be counseled preoperatively to expect improvement in gastrointestinalsymptoms but not necessarily complete relief after LC for cholecystitis.4. Clinicians should be concerned about the possible emergence of bile reflux gastritisand diarrhea after LC.