The Clinical Significance Of Serum Transaminase In Diagnosis And Classification Of Liver Injury After Abdominal Closed Injury

Objective:To study the clinical significance of serum transaminase in diagnosis and classification of liver injury after abdominal closed injury. Methods:From February2011to November2013,95diagnosis cases of abdominal closed injury were collected and divided into liver injury group(48cases) and non-liver injury group(47cases). Detecting the value of glutamic-pyruvic transaminase(ALT),glutamic-oxalacetic transaminase(AST), lactic dehydrogenase(LDH), gamma-glutamyl transpeptidase(GGT), bilirubin and total white blood cells(WBC) to study the correlation between the value and the liver injury occurrence and classification. Results:Using ROC curve assessment,optimum ALT, AST thresholds were determined to be>47U/L and65U/L. ALT>47U/L and AST>65U/L were associated with the presence of liver injuries. The values of AST, AST and LDH in the liver injury group were significantly higher than those in the non-liver injury group(P<0.01). In liver injury group, the values of AST, AST and LDH in severe group increased significantly than mild group(P<0.01). The values of GGT, Bilirubin and WBC in liver injury group have no significantly differences which were compared with the non-liver injury group. They also have no significantly differences between severe group and mide group. Conclusion:The value of AST and ALT are still the effective index in diagnosis and evaluating the classification of liver damage, which providing clinical doctors with detailed and reliable gist to take proper treatment measures for patients.