The Study On The Changes Of Macular Retinal Thickness And Volume In Diabetic Retinopathy After Panretinal Photocoagulation By OCT

Objective:In this study we select patients with diabetic retinopathy and macular edema and all of them received Panretinal Photocoagulation.Topcon 2000 3D OCT examination was performed to observe and analysis the retinal thickness and macular volume changes in the macular area,so we can assess the effect of laser treatment.Methods:Case control study was conducted in 24 patients(38eyes) with Diabetic retinopathy between January 2014 and September 2014,including 24 eyes with severe non-proliferative diabetic retinopathy(NPDR), 14 eyes with proliferative diabetic retinopathy(PDR).All patients received Panretinal Photocoagulation in three times.Topcon 2000 3D OCT examination was performed to observe and analysis the retinal thickness and macular volume changes in the macular area before PRP, the first week 、 the first month 、 the third month after PRP.We used SPSS17.0 statistical software to analysis of these clinical data.Results:At the first week 、 the first month 、 the third month after the PRP finished,significant increasing of average macular thickness, A1-A9 retinal thickness,foveal retinal thickness and macular volume of the total increase was observed, the difference was statistically significant(P <0.05).The most extend of macular thickness increasing was found in the first month.At three month after PRP,the retinal thickness was decreasing.Conclusion:(1)OCT can show the changes after PRP,and assess the effect of PRP accurately.So OCT can be applied to the follow-up of diabetic retinopathy.(2)PRP can cause macular edema in the short term,but as time goes on, macular edema was gradually reduced, retinal function was gradually restored.(3)Diabetic retinopathy with limited macular edema is still thin in center of the macula, thick around the macula which looks like the valley, and the temporal area of the retina is the thinnest.In the early period after PRP,the macula still looks like the valley.(4)PRP can control the progression of diabetic retinopathy,and it is the effective treatment of diabetic retinopathy.