Clinical Research On Acupuncture Treatment Of Yin Deficiency And Yang Hyperactivity Syndrome And Excessive Accumulation Of Phlegm-dampness Syndrome Of Essential Hypertension

Objective: To explore the clinical efficiency of the acupuncture treatment for Yin deficiency and Yang hyperactivity syndrome and excessive accumulation of phlegm-dampness syndrome of primary hypertension. Methods: Cases were divided into the therapeutic group and the matched group by a central method of randomization. The treatment group was treated with electroacupuncture meridian points, while the control group was going through electroacupuncture non-meridian points. Observed the efficacy after eighteen times, and then carefully analyzed the data statistic. Results: 20 cases of the treatment group and 20 cases of the control group.1. Analyzed two groups of efficacy of depressurization: the total clinical efficacy rate of the therapeutic group was 90.00% and the matched group was 70.00%. There was 2. Analyzed the two groups efficacy of symptom scores, the total effective rate of the therapeutic group was 95.00%, and that of the matched group was 80.00%. There was a highly significant difference between two groups(P<0.05).3. There was a extremely remarkable difference in both groups in improving the symptoms(P < 0.01). Compared after the treatment, there was a outstanding difference between two groups(P<0.01).4. The evaluation of therapeutic efficiency of 24-hour Ambulatory Blood Pressure Monitoring(ABPM)⑴ Intra-group comparison:Comparison 24 hours of Systolic Blood Pressure(SBP) and Diastolic Blood Pressure(DBP) between the treatment group and the control group of average SBP and average DBP compared between before and after the treatment group and comparison, reached a highly significant(P<0.01);Comparison of day(06:00-22:00)blood pressure, the treatment group for the average SBP and the average DBP has a very significant difference(P < 0.01);the control group for the average SBP has a significant difference(P<0.05), for on the average DBP, in decreasing of average SBP the two groups showed no statistically significant(P>0.05);After treatments, compared with average SBP and average DBP at night(22:00-06:00) between the treatment group and the control group, the treatment group for the night average SBP and average DBP achieved a very significant difference(P<0.05), for the night average SBP and DBP, the control group was not achieved significant levels(P>0.05).For the 24-hour of average SBP of Yin Xu Yang Kang and retention of phlegm and dampness, the treatment group for them between before and after therapy was statistically significant(P<0.05),for the retention of phlegm and dampness, the control group for it between before and after therapy was not statistically significant(P>0.05), For the Yin deficiency and Yang hyperactivity, the control group treatments between before and after therapy was statistically significant(P<0.01); the treatment group for the 24 hour average SBP of Yin Xu Yang Kang and retention of phlegm and dampness was statistically significant(P<0.01), the control group for the two syndrome types was no significant difference(P>0.05); Compared with 24-hour average DBP of(P>0.05)and abundant accumulation of phlegm and dampness between the treatment group and comparison, after the treatments.For the 24 hours average SBP of retention of phlegm and dampness, the treatment group for it between before and after therapy was not statistically significant(P>0.05), for the two syndrome types, the control group treatment was no significant difference(P>0.05); After treatments, the two groups for the two syndrome types was not statistically significant(P>0.05).⑵ Compare among groups:After treatment, comparison of average SBP and average DBP between the treatment group and the control group, the difference had a statistically significant(P<0.01),The comparison of average of DBP between the treatment group and the control group, the difference had no statistically significant(P>0.05). Comparison of the average SBP and the average DBP between the points and the non points were statistically significant(P < 0.05), and in decreasing of average DBP was not significant levels(P>0.05).The two groups for the night average SBP and DBP were not statistically significant(P>0.05).Comparison of 24-hour average SBP of the Yin deficient Yang stimulation and excessive accumulation of phlegm dampness between the treatment group and the matched group were not statistically significant(P>0.05).After the treatments, comparison of 24 hours of average SBP of the yin deficiency and yang hyperactivity and retention of phlegm and dampness between the treatment group and the control group were not statistically significant(P>0.05). 5 Laboratory data treatment: High Sensitivity C-Reactive Protein(Hs-CRP) and Interleukin-6(IL-6) ⑴Intra-group comparison:Compared with serum Hs-CRP and IL-6 between before and after of the treatment group was outstanding statistically significant(P<0.01), the matched group for serum Hs-CRP and IL-6 had no statistically significant(P>0.05); For the Hs-CRP of two syndrome types, the treatment group for it between before and after therapy was statistically significant(P<0.01), for excessive retention of phlegm and dampness, the control group treatment was not statistically significant(P>0.05), for the yin deficiency yang excessive, the control group treatment was marked significant difference(P<0.01); After treatments, the two groups for the two syndrome types was not statistically significant(P>0.05);For the IL-6 of two syndrome types, the treatment group for it between before and after therapy was statistically significant(P<0.01), for the retention of phlegm- dampness, the control group treatment has no statistically significant(P>0.05), for the yin deficiency yang hyperactivity, the control group treatment result was extremely statistically significant(P<0.01); After treatments, the two groups for the two syndrome types was not statistically significant(P>0.05); comparison of IL-6 of and retention of phlegm and dampness between the therapeutic group and the control group showed statistically significant(P<0.05), for the IL-6 of the Yin deficiency and Yang hyperactivity between the treatment group and the control group showed no statistically significant(P>0.05). ⑵ Compared between groups:Comparison of serum Hs-CRP and serum IL-6 between the therapeutic group and the control group not reached significant(P>0.05).Comparison of Hs-CRP of retention of phlegm and dampness between the treatment group and the control group showed statistically significant(P<0.05), for the Hs-CRP of the Yin deficiency and Yang hyperactivity between the treatment group and the control group showed no statistically significant(P>0.05).Compared with serum Hs-CRP and serum IL-6 between the treatment group and the matched group were not significant levels(P>0.05). Conclusion: 1. The results show that the meridian points acupuncture treatment compared with non-meridian points acupuncture is more effective about reduce the level of blood pressure and improvement of clinical symptoms; and the treatment group effect is superior to the control group.2. The treatment group in improving the average SBP of 24-hour and daytime is better than the control group. The treatment group in improving the retention of phlegm and dampness on average SBP of 24-hour is better than the Yin deficiency and Yang hyperactivity, for the day average DBP has no difference. 3. The treatment group in improving the accumulation of phlegm-dampness of serum Hs-CRP better than the Yin deficiency and Yang hyperactivity.The treatment group and the control group in improving the retention of phlegm and dampness of serum IL-6 is better than the placebo group.