Study On The Related Factors Of The Quality Of Life And Subjective Symptoms Of Patients’ With Hysteromyoma

Background and ObjectiveUterine fibroids is a common benign gynecologic tumor, which has a lot of different clinical symptoms such as menometrorrhagia, lower abdominal mass, problems of urination,and disfuction of defecation [1].About 20% of women over 35 years old are suffering from uterine fibroids. Because of no significant self-symptoms, most women with uterine fibroids have not received any treatment early, even without any treatment [2-4]. The main treatment of uterine fibroids is surgery. However, both disease itself and the damage of surgery would bring more pressure in mental, would affect women’s mental health and life’s quality [3].Physical-psychology-social medical model is the modern medical mode, which thinks people as objects of medical research, not only the organic entity made up of various tissues, but also a complex member of society with various psychological activities. All poor mental stimulation, inappropriate style of life, poor behavior, or harmful environmental factors could lead to the occurrence of diseases. More and more clinical doctors have paid more attention on the comprehensive comprehension of patients, especially their mental health status [3].So far, there are many studies on the quality of life or subjective symptoms of patients with hysteromyoma abroad. However, research on the psychological status of patients with uterine fibroids is still rare in China.This study collected medical records in a three-Armour hospital in Shanghai between May 2010 and May 2014. It aimed to analyze the basic situation of patients with uterine fibroids, and to find out their subjective symptoms in common, and to evaluate their quality of life, and to explore the risk factors of hysteromyoma. The present study aimed to provide some scientific proofs for the prevention and treatment of uterine fibroids.Materials and Method216 patients with uterine fibroids treated in a three-Armour hospital in Shanghai between May 2010 and May 2014 were collected as the case group and another 216 cases as control randomly over the same period in hospital, who had similar professional and cultural level, the difference of ages was less than 3 years, and ruled out the other disease by ultrasound. The matching ratio between the case group and the control group was 1:1 in the aspects of the age and profession and cultural factors. The diagnostic criteria of uterine fibroid [3] contained three conditions as follow:(1) The profuse menstruation, menstrual extension or irregular vaginal bleeding; (2) The plevic examination can touch the uterine fibroids nodules; (3) Ultrasonic examination can show images of myoma.The general information of the two groups included demographic data, marital and reproductive history (marital status, number of brady, birth, abortion, lactation, etc.), family history (relatives with malignancy, first and second level history relatives of uterine fibroids), medical history and so on. Self-made questionnaires were used to collect patients’physical exercise, diet, personality, negative life events and so on. Eysenck personality questionnaire (EPQ), SCL-90 symptoms self evaluation scale, life quality comprehensive assessment questionnaire, psychological and sexual life quality scale were used to assess patients’quality of life index. Using case-control study method, the single factor analysis and conditional logistic regression were taken to analyze the patients’data to explore the pathogenesis and the related risk factors of uterine fibroids.ResultThis study showed that patients with uterine fibroids had taken high proportion in the department of gynecology every year from 2010 to 2014, all of which above 13%, and the average rate was 14.89%. However, the proportion of 3.93% benign tumor, carcinoma in situ, malignant tumor and secondary tumor, adenocarcinoma and other gynecological tumor in gynecological disease. The treatment fee of uterine fibroids in 2014 was 11260.8516 Chinese Yuan per person.Compared with various factors, patients with hysteromyoma showed some psychological problems measured by SCL-90. Part of them had kind of psychological terror, such as fearing of tumor progression, being afraid of surgery, fearing the disease would affect sexual life after hysterectomy and so on.80.09%(173/216) patients with uterine fibroids received the survey because of different self-symptoms, only 19.91% people were found during medical check without dysfunction. There were 51 patients with only a kind of self-conscious symptom,63 patients having two kinds of self-conscious symptom,29 patients with three kinds of self-conscious symptom,30 patients with more than four kinds of self-conscious symptom. The survey results indicated that patients with increased uterine size easily appeared more subjective symptoms and severity compared with patients with normal uterine size.Single factor and unconditioned logistic regression analysis found that both late marriage age and many times abortion affect the occurrence of the disease, but the long accumulative time of lactation can obviously reduce the risk of uterine fibroids. This study also found that women who ate soy regularly can reduce the risk of uterine fibroid. Women with mammary gland hyperplasia, chronic gynecologic inflammation disease, having a family history of malignant tumors, with first-degree relatives of patients with uterine fibroids could increase the risk of uterine fibroids, and secondary relatives in patients with uterine fibroids had nothing to do with the onset of uterine fibroids. Uterine fibroids were the result of multiple factors, such as both pelvic inflammation, and cervical erosion would induce the increased secretion of epidermal growth factor locally, leading uterine fibroids.ConclusionUterine fibroids have taken a high proportion of benign gynecological tumors. The disease not only reduced the quality of life of patients, but also bought economic loss to their family and society.Patients with hysteromyoma were more prone to menstrual problems, such as bleeding, pain, oppression. There was no direct relation between the patients’ age, occupation, the size of uterus and self-conscious symptoms.Late marriage age, number of miscarriage, hyperplasia of mammary glands, chronic inflammation of department of gynecology disease, having a family history of malignancy, first-degree relatives of patients with uterine fibroids could increase the risk of uterine fibroids.Long accumulative lactation time could obviously reduce the risk of uterine fibroids, and secondary relatives in patients with uterine fibroids had no matter with the onset of uterine fibroids.