| ObjectiveThis study discussed the Chinese Medical information of 144 elderly patients with KOA about the Syndromes of Traditional Chinese Medicine by cluster analysis and other statistical methods. Not only had it studied the clinical distribution about Syndromes of Traditional Chinese Medicine, but also the relationship among the scores of WOMAC, VAS and the degrees of SDS.MethodsThis study contained 144 elderly patients with KOA who meet the criteria of the Guidelines for the diagnosis and treatment of Osteoarthritis in the First Affiliated Hospital and the Third Affiliated Hospital of Guangzhou University of TCM from October 2013 to March 2015. Firstly, questionnaires of Syndromes of Traditional Chinese Medicine are made by experts, which are used to collect the Chinese Medical information and the scores of WOMAC,VAS and the degrees of SDS about 144 elderly patients. Furthermore, the related statistical data is analyzed by the above statistical methods in order to induce the clinical distribution about Syndromes of Traditional Chinese Medicine and the relationship among the scores of WOMAC, VAS and the degrees of SDS.Results1.This study contained 51 male and 93 female patients in 144 elderly patients with KOA whose average age was 80.19±3.99 years old, and the minimal age was 75 years old and the maximal age was 93 years old. This ratio of sexy was about 1:2.The Chinese Medical information of 144 elderly patients with KOA had been classified three patterns:Syndrome of deficiency of liver-yin and kidney-yin, Syndrome of stagnation of liver-qi and deficiency of the kidney, Syndrome of yang deficiency of spleen and kidney. And the first pattern contained 65 cases, accounting for 45.14%;the second pattern contained 56 cases, accounting for 38.89%;the last pattern contained 23 cases, accounting for 15.97%. The first kind of Syndrome of TCM is characteristiced by indistinct pain of knee, pain of waist and knee, dysphoria with feverish sensation in chest, hectic cheek, tinnitus, vertigo, night sweating, frequent micturition, astriction, red tongue, less coating on the tongue, thread rapid pulse. The second kind of Syndromes of Traditional Chinese Medicine is characteristiced by stabbing pain of knee, fixed pain of knee, soreness and weakness of waist and knees, depression, irritability, distending pain in hypochondrium, frequent suspiration, epicophosis, dry eyes, the sense of suppression in the chest, insomnia, the dry and bitter taste, dark red skin, dim tongue with suggillation and petechia, thin tongue with thin and greasy fur, thready pulse, acrostic pulse, thin and string pulse.The third kind of Syndromes of Traditional Chinese Medicine is characteristiced by cold pain of knee, acid pain of knee, night pain of knee, aggravation of pain in overcast and rainy weather, fatigue, bland face, fear of cold and cold limbs, numbness of limbs, heaviness of limbs, in-appetence, tastelessness, clear urine in large amounts, loose stool, plump and teeth-printed tongue, string slippery and slow-sunken pulse.2. This study analyzed the scores of WOMAC in patients by SNK test whose result of ANOV test was significant(P<0.05), and found the results of SNK test were significant (P<0.05). Furthermore, the statistic relationship among the three kind of Syndrome of group of Syndrome of TCM was significant(P<0.05). This study analyzed the scores of WAS in patients by K-W rank-sum test whose result of ANOV was not significant (P<0.05), and found the results of K-W rank-sum test were significant(P<0.05). Furthermore, the statistic relationship among the three kind of Syndrome of group of Syndrome of TCM was significant(P<0.017) by rectifying the acceptance standard. At last,the statistic relationship about the degrees of SDS were significant (P<0.05), which revealed the statistic relationship between the group of Syndrome of yang deficiency of spleen and kidney and the group of deficiency of liver-yin and kidney-yin was not significant(P>0.017). When the group of Syndrome of stagnation of liver-qi and deficiency of the kidney compared with the group of Syndrome of yang deficiency of spleen and kidney and the group of deficiency of liver-yin and kidney-yin respectively, the statistic results were significant(P<0.017).Conclusion1. This study found three kinds of Syndrome of TCM:Syndrome of deficiency of liver-yin and kidney-yin, Syndrome of stagnation of liver-qi and deficiency of the kidney, Syndrome of yang deficiency of spleen and kidney. The Syndrome of deficiency of liver-yin and kidney-yin is the most common of the three patterns, and the Syndrome of stagnation of liver-qi and deficiency of the kidney is more common than the Syndrome of yang deficiency of spleen and kidney. The core pathological mechanism of this diseaseses is deficiency of the kidney, and the dysfunction of liver and spleen is the important segment.2. This study analyzed the scores of WOMAC in patients, and found the results were significant. Furthermore, the statistic relationship among the three kind of Syndrome of group of Syndrome of TCM was significant. This study analyzed the scores of WAS in patients and found the results were significant. Furthermore, the statistic relationship among the three kind of Syndrome of group of Syndrome of TCM was significant. At last, the statistic relationship about the degrees of SDS were significant, which revealed the statistic relationship between the group of Syndrome of yang deficiency of spleen and kidney and the group of deficiency of liver-yin and kidney-yin was not significant. When the group of Syndrome of stagnation of liver-qi and deficiency of the kidney compared with the group of Syndrome of yang deficiency of spleen and kidney and the group of deficiency of liver-yin and kidney-yin respectively, the statistic results were significant. |
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