The Exploratory Study About The Specification And Pre- Evaluation For Prescription Of Chinese Medicine

Objective:The practical exploration of law of traditional Chinese medicine in prescription compatibility of prescriptions of traditional Chinese medicine, the mathematical expression of traditional Chinese medicine informatization method and basic data, clinical prescription in TCM from the specification, finding solutions in the process of TCM clinical prescribing subjective, the lack of norm constraint, the writing is illegible, the dosage of the drug usage is unknown, the abuse of medicine, incompatibility and issued large prescription, irrational prescriptions and many other issues, the construction of a pre evaluation model based on the prescription of TCM clinical evaluation system, and practice using the means of information.Methods:1. The use of literature analysis and system analysis method of study of traditional Chinese medicine clinical prescription specification, through the collection and traditional Chinese medicine prescription for literature, Chinese medicine prescription compatibility theory data, ancient and modern literature in each other, medicine, card of the relevant discussion of data, study the relationship between them, take all factors influencing the clinical doctor of Chinese medicine prescription of as the research object, the research object is placed on the system form, starting from the whole and the overall situation, methods, clear logic can describe all transformed into rules, elements will be able to quantify all the abstracted as mathematical variables, and lay the foundation for the Chinese medicine clinical technology layer prescription standardized operation.2. Construction of evaluation model theory 2 the use of artificial intelligence algorithms, the abstract method into algorithm, the compatibility law of TCM prescription analysis summary data and evaluation of prescription mode of thinking with a mathematical model to describe, so that the computer can through the arithmetic operations, logic operations, relational operation to achieve recognition and calculation for clinical prescription the doctor of traditional Chinese medicine.3. To use the waterfall model of software engineering field, the selection of international Delphi language, combined with FastReport 4 a report model development of clinical Chinese medicine prescription evaluation of special software--clinical Chinese medicine prescription pre evaluation system.4. To use the ontology thought constructing TCM clinical prescription and TCM basic knowledge of terminology, concepts and their attributes and relationships described as one of the elements of the segmentation, find out the basic vocabulary and concepts of TCM clinical prescription and TCM basic knowledge in similar terms and concepts, will be converted to class, use the rules of abstract the text data in the establishment of class and the concept of contact under restricted conditions, information operations so that the data is possible.Results:1. Through the analysis of literature of traditional Chinese medicine prescription, found the existing norms are more concentrated in writing and administrative levels of prescription, lack of technical specifications. From the point of view that the scope of clinical Chinese medicine prescription specification should be increased to prescription safety, validity, rationality, indications and potential adverse events and other aspects of the content, standard formulation and implementation of quality evaluation of traditional Chinese medicine is a clinical diagnosis and the areas of urgent need, is the main technical means of prevention of medical accident. This study will be divided into basic requirements, specification format specification, specification writing, content standard, technical specification, unreasonable prescription evaluation standard of six parts, the key lies in the standard prescription content of qualitative and quantitative constraints, required party content based on satisfying the basic format should be consistent with the recipient people physical condition, able to reflect on the treatment of TCM thought.2. Through the analysis and study of the Chinese modern literature, the compatibility law of monarch drug resistance of seven methods in prescription compatibility, compatibility, compatibility, compatibility, prescription drugs on the compatibility of prescriptions of traditional Chinese medicine core of addition and subtraction were sorted out, proved that traditional Chinese medicine prescription is plausible, is "in traditional Chinese medicine science, law, parties, drugs" theory system to guide under the. The doctor of traditional Chinese medicine prescription can be traced to the syndrome type and the physical condition of patients, which is an important application of "test with a prescription" point of view, is the theoretical basis of TCM clinical prescription standard, Chinese medicine practitioners should be able to make a reasonable interpretation of the prescription of each drug use.3. In the TCM clinical prescription norms in the process of research, the qualitative and quantitative constraints on the prescription to make text content as follows:should be clear that the drugs at their own expense, part pays drugs and prescription drug used alone pays in the body; the term of validity of prescription should be clearly identifies the prescription; prescription drug indications should be matched with the prescription diagnosis otherwise, judged to be unreasonable prescription of Chinese medicine Yinpian prescription drugs; single agent in the total number of not more than 20 flavor; Chinese medicine Yinpian prescription drugs in single machine total quality of not more than 300 grams; Chinese herbal medicine prescription if containing eighteen-, nineteen fear of compatibility, excessive toxic drugs, physicians should sign again in the corresponding medicine; not repeated administration of the phenomenon; no justification for the same patients also issued more than two kinds of pharmacological effects of the same drug prescription.4. According to the prescription of the traditional Chinese clinical norms, studied the clinical prescription pre evaluation of TCM schemes, this scheme can in physician prescribing, patients receive pre prescription according to the specification of clinical prescription in TCM pre evaluation, so that every doctor can prescribe specifications, reasonable, and reliable prescription, to realize the control of clinical Chinese medicine prescription quality the. This study is to design three kinds of clinical prescription pre evaluation pattern of traditional Chinese medicine, namely the accurate evaluation, objective evaluation, the reference evaluation.(1) The accurate assessment is through the analysis of clinical prescription in TCM, using classical prescription recognition algorithm based on exhaustive method to find the complete classic formula contains a clinical medicine in the prescription, lists the corresponding to all the classic prescription of clinical application scope, the symptoms or diseases with traditional Chinese medicine treatment of common clinical manifestation, symptom or disease, analysis western medicine disease which may correspond to. At the same time, also from the accurate evaluation of prescription in the presence of eighteen anti, nineteen fear, toxic drugs, drug potential hazards in four aspects analysis, combined with the specific techniques for clinical prescription in TCM in the specification on the side of safety, rationality and adapt to evaluate the symptoms of disease.(2) The objective evaluation is through the analysis of all drug types and doses of the drug in the prescription drug, weighted by their corresponding prescription principle and effect of the prescription, and the safety and rationality of objective evaluation, this part by prescription treatment range evaluation and Chu Fangan safety and rationality of prescription, prescription analysis, function prediction five modules, and accurate evaluation part is different, the objective evaluation of prescription treatment range evaluation part modules listed application syndrome in all drug prescriptions; prescription safety evaluation in the eighteen counter and analyzing the nineteen fear and toxic Chinese medicine lists all drug use matters needing attention; prescription analysis the types of drugs and drug weighted drug types of monarch drug effect of the prescription, and can judge out the adjuvant drug types; effect forecast lists all the effects of drugs, and provide both reference.(3) The reference evaluation by analysis of clinical prescription, using template matching rules to find out which contains all incomplete classical prescription, and thus on the prescription of safety, rationality and adaptive symptom disease pre evaluation. Constitute the part by prescription treatment range evaluation, prescription safety and rationality of prescription, prescription analysis, function prediction of five big modules. And the accurate evaluation of part is different, the reference evaluation prescription treatment range evaluation part module analyzes the incomplete cure disease and symptom of the classic prescription; prescription composition analysis module for clinical prescription of incomplete prescription drug name, in accordance with the 90% principles; efficacy prediction module according to the prescription contains all incomplete prescriptions. Analysis of the corresponding function.5. In the ontology thought under the guidance of basic TCM data were digitized, with the distinction between prescriptions of traditional Chinese medicine, TCM, TCM diagnosis, TCM Department of internal medicine etc. the content of TCM knowledge attribute, the TCM clinical prescription and TCM basic knowledge is divided into the classical prescription data, traditional Chinese medicine, traditional Chinese medicine disease data data and clinical prescription data of four categories, to establish mutual contact through foreign keys, construction of TCM information model, created the clinical standard of traditional Chinese medicine and evaluation database, currently contains data 1672.6. According to the evaluation module design requirements of TCM prescription evaluation content of classical prescription recognition algorithm based on exhaustive method and calculated based on the resistance weighted algorithm, can be the prescription of traditional Chinese medicine traditional Chinese medicine clinical and basic knowledge into the matrix and vector, identified and calculated by mathematical models.7. Using the method of software engineering design and development of traditional Chinese medicine clinical prescription pre evaluation system, the main functions of the system include:implement electronic entry clinical prescription drug, dose; can the accurate evaluation of clinical prescription of traditional Chinese medicine, on any objective evaluation, the reference evaluation; can output multiple formats result report, can achieve the result of report; can the realization of digital storage and display of Chinese traditional medicine, Chinese traditional medicine knowledge and knowledge of Chinese medicine discipline knowledge. Including the technical features of the system:by using the method of relational database technology to realize knowledge of traditional Chinese medicine prescriptions of traditional Chinese medicine, traditional Chinese medicine knowledge and digital storage of subject knowledge; realize the accurate pre evaluation and reference of clinical Chinese medicine prescription arbitrary pre evaluation using classical prescription identification technology; traditional Chinese drug weighted algorithm using objective evaluation of clinical prescription of TCM pre arbitrary use statements; the output pre assessment tool.Conclusions:1. By TCM clinical prescription specification in the specific safety, rationality, technical specification requirements, realizes the quantitative evaluation of prescription of safety, rationality, scope of application.2. Chinese medicine "science, law, parties, drugs" theoretical system as a benchmark, prescription, drug cut, indications of source, indications, efficacy, use method or traditional Chinese drug weighted calculation etc to evaluate the prescription, prescription evaluation model construction of new.3. Through the study of TCM clinical prescription standardization and prescriptions of traditional Chinese medicine compatibility law of TCM clinical prescription, constructed a mathematical model based on matrix and vector, the realization of the information processing in clinical prescription of traditional Chinese medicine, can through quantitative means basis for evaluation of rapid, objective, impartial evaluation algorithm of prescription.4. The uses the theory of ontology based knowledge of traditional Chinese medicine will be divided into basic elements, the use of relational database established association of traditional Chinese medicine basic knowledge and clinical application of traditional Chinese medicine prescription and the realization of the information stored on the basis of the mathematical model, using the software engineering method to establish the TCM clinical prescription evaluation platform, physicians prescribing can be on the platform in advance the prescription evaluation, with the evaluation report to judge the prescription can deliver patients to achieve the desired effect and no responsibility for security issues, embodies the value and significance of clinical Chinese medicine prescription specification, provides an important reference for the objective of TCM diagnosis and treatment in the future, standardization, information research work.