Research On The Effects Of Acupuncturing Left Side Xiaxi Acupoint (GB43) On ICA Blood Flow And PI And RI Values In Patients With Vertebral Basilar Artery Type Transient Ischemic Attact

Purpose:By observing with TCD ultrasonic instrument the changes in TIA patients’ posterior cerebral artery peak systolic blood flow velocity (Vs), average blood flow velocity (Vm), diastolic blood flow velocity (Vd), resistance index (RI) and pulse index (PI) when Xiaxi acupoint (GB43) on the left side is acupunctured, this thesis explores the effect on PCA blood flow velocity and on PI, RI five minutes before acupuncturing Xiaxi acupoint on the left side, when needling in, retaining the needles for 15 minutes, retaining the needles for 30 minutes, withdrawing the needles and five minutes after withdrawing. The results would be helpful in choosing acupuncture points for the treatment of TIA patients.Methods:30 TIA patients from The First Affiliated Hospital of Heilongjiang University of TCM are chosen as research object. Their ages range from 39 to 69, average 52.57±10.05; 19 of them are males,11 females; 14 of them suffer from hypertension,5 diabetes,2 coronary atherosclerotic heart disease,7 hyperlipidemia,9 cases of cervical spondylosis. Essentials of diagnosis in TIA made by the Chinese Medical Association in 1996 the Fourth National Conference on Cerebrovascular Disease is adopted as western medicine diagnostic criteria, and diagnostic criteria in textbook by National Colleges and Universities of TCM Chinese Internal Medicine is adopted as Chinese medicine diagnostic criteria. The experiment begins after the patients understand the purpose of this experiment, methods, processes, and the problems need to pay attention to and agree to do so. Lab environment includes room temperature 22 ±3 ℃, humidity 50±5%, and the experiment time is always set at 6 PM to 7 PM. The detected are asked to keep to supine position, head to the side so that the tempus can be fully expose. The probe of Companion III TCD made by German EME Company whose transducer frequency is 1.6MHz is put above patients’ zygomatic arch to examine the posterior cerebral artery, detecting depth 60-65mm. The PCA’s Vs (systolic maximum blood flow velocity), Vd (end-diastolic blood flow velocity), Vm (average blood flow velocity), PI (pulsation index) and RI (impedance index) value are recorded after the image become stable. After the patients’take a 10 minutes quite rest, the blood flow velocity and PI、RI five minutes before needling in, when needling in (acuesthesia and twisting the needles for 15 seconds), retaining the needles for 15 minutes(15 seconds after twisting the needles), retaining the needles for 30 minutes(15 seconds after twisting the needles), withdrawing the needles (having retained the needles for 45minutes and 15 seconds after reinforcing-reducing method twisting)and five minutes after withdrawing is observd. Put the data from these six points-in-time into SPSS 17.0 statistical system, establish the database, and use single-factor variance analysis method to analyze. If P<0.05, the data is statistically significant.Results:1.The effect on the left posterior cerebral artery’s Vs, Vd and Vm if the left side of the GB43 is acupunctured.If the left side of the GB43 is acupunctured, the parameters of Vs、Vd and Vm when retaining the needles for 15minutes and 30minutes are: 89.60±10.972.86.43±11.428,49.10±7.246.46.13±7.736,62.53±8.212,59.57 ±8.549. All are higher than the parameters of Vs、Vd and Vm five minutes before needling in thus are statistically significant (P<0.05). Parameters on the left side in other points-in-time do not show much difference compared to five minutes before needling in, and the SPSS17.0 statistical analysis shows it is not statistically significant(P>0.05).2.The effect on the left posterior cerebral artery’s PI and RI if the left side of the GB43 is acupunctured.If the left side of the GB43 is acupunctured, the value of PCA’s PI and RI on the left side when retaining the needles for 15minutes, for 30 minutes, withdrawing and five minutes after withdrawing are not significantly different compared to five minutes before needling in thus has no statistical significance according to the SPSS17.0 system (P>0.05).3.The effect on the right posterior cerebral artery’s Vs, Vd and Vm if the left side of the GB43 is acupunctured.If the left side of the GB43 is acupunctured, the value of PCA’s parameters on the right side when retaining the needles for 15minutes, for 30 minutes, withdrawing and five minutes after withdrawing get higher compared to five minutes before needling in, but the SPSS 17.0 statistical analysis shows it is not statistically significant(P>0.05).4.The effect on the right posterior cerebral artery’s PI and RI if the left side of the GB43 is acupunctured.If the left side of the GB43 is acupunctured, the value of PCA’s PI and RI on the right side when retaining the needles for 15minutes, for 30 minutes, withdrawing and five minutes after withdrawing are not significantly different compared to five minutes before needling in thus has no statistical significance according to the SPSS 17.0 system (P>0.05).Conclusions:1. Acupuncture on the left side of the GB43 can cause an increase in PCA’s blood velocity on the left side when retaining the needles for 15minutes and 30minutes.It shows accumulative effect and modulate positively without after effect, but it has nothing to do with vascular compliance. This indicates that when the TIA patients’blood flow slows down, acupuncture on the left side of the GB43 is favorable.2.Acupuncture on the left side of the GB43 has no effect in any point of time on the right side of PCA’s vascular compliance and vascular tone.3.Reducing the time of retaining the needles to a proper value is advised.