Clinical Observation Of Percutaneous Radiofrequency Ablation Of Spleen With Splenic Artery Balloon Block For The Treatment Of Hypersplenism

Objective: To investigate the clinical effect and experience of splenic artery balloon block combined with percutaneous radiofrequency ablation (RFA) for hypersplenism patients due to liver cirrhosis and portal hypertension.Methods:RFA was performed in 15 hypersplenism patients complicated with liver cirrhosis and portal hypertension. The routine blood count was monitored periodically after RFA 3 days,7 days,1 month,3 months and 6 months, abdominal CTA was performed after RFA one month. Result: One patient occurred massive bloody pleural effusion after RFA three days, the condition improved after splenic artery embolization and drainage of pleural effusion. The splenic volume after ablateing was accounting for about (34.3%-71.8%) of spleen before RFA, the mean volume was (56.20±13.09)%. The count of white blood cells, red blood corpuscle and blood platelet was (3.88±1.75)×109/L,(4.06±0.37)×1012/L, (48.14±11.33) ×109/L, respectively. One month later, the count of white blood cells and blood platelet rised to (5.62±1.61)×109/L and (132.29±33.20)×109/L, The count of white blood cells and blood platelet after RFA were statistically significant in comparison with them prior to RFA (P<0.05). Conclusion:Splenic artery balloon block combined with percutaneous radiofrequency ablation(RFA) is a safe and effective treatment for hypersplenism patients due to liver cirrhosis and portal hypertension.