Associations Research Between Type A Behavior Pattern And Polycystic Ovary Syndrome

Background:Polycystic ovary syndrome (PCOS) is very common and affects 5’10% of young women, which 75% of them has reproductive dysfunction. The disease affects women’s body and psychology health badly. The reason and mechanism are still unknown, but adverse events and dissatisfaction have already been proved to be a main cause to PCOS. They have low quality of life, slight depression and anxiety. Type A behavior pattern (TABP) which characterized by extreme sense of time urgency, competitiveness, impatience, and aggressiveness. This character makes body in a chronic stress state, excessive sympathetic nerve tension which makes the immune and neuroendocrine disorder. If this condition last, it would bring about many disease. The researches have proposed as an independent risk factor for coronary heart disease, hypertension, myocardial infarction and premature ovary failure. On the basis of form research, propel us to think that are there any relationships between TABP and PCOS? Can TABP affects PCOS life satisfaction, metabolism and the type of traditional Chinese medicine syndrome (TCM)?Objective:To find out its distribution in PCOS, and the relationship among etiology, type of TCM, metabolism and life satisfaction.Method:We recruit patients with PCOS who come from outpatient department. Record patients age, menstruation, height, weight, education history and occupation. Measure hirsutism, acne and acanthosis nigricans by professional staff. Patients wright down the type A behavior pattern questionnaire (TABPQ) which was established by Boyuan Zhang, main syndrome, the Chinese quality of life scale, LH, FSH, PRL, T, DHEAS, AND, SHGB, FG and FINS, calculating the HOMA-IR (FG×FINS/22.5).The LH、FSH、PRL、 T are measured during the day 2-7 of menstrual cycle. We have 100 cases in control group. These normal women who come from junior high school, university and accompanies from outpatients department need fill TABPQ only. The two groups were matched for age, education and occupation.The data were filled in Excel and analyzed in SPSS21.0. If the data is normal distribution using one way ANOVA or using non-parametric instead, including Chi-square and Stepwise regression analysis as well. The PCOS are divided into groups by the score of TABP, A group and non-A.Results:1. The distribution in PCOS group between control group are equal.2. There is no statistical significance in the distribution at A group and non-A group in PCOS, as well as in sex hormone, androgen, HOMA-IR, hairiness and acanthosis nigricans.3. There are statistical significance in life satisfaction, acne and BMI in A group and non-A group, p<0.05.4. The Stepwise regression analysis show that TABP scores were positive associated with acanthosis nigricans, and weight.Conclusion:1.The distribution in PCOS and normal women are nearly equal.2.TABP lower the PCOS patients life satisfaction. TABP exacerbations PCOS patients’ acne, BMI, and shows positive associated with acanthosis nigerians and weight. But TABP has no impact on PCOS patients’ sex hormone, androgen, glucose metabolism.3.The main TCM in PCOS with TABP are kidney-asthenia and liver depression.