Study On Modeling Of The Bionic Bone Tissue

The damage and defect of human tissue will lead to dysfunction. Repair with autologous tissue grafting, although we can achieve a satisfactory effect, but it is the way to the expense of autologous healthy tissue will lead to many complications and additional damage. Human organ failure, drug therapy, temporary replacement therapy could save the lives of some patients, but the source of donor organs is extremely limited, due to immune rejection requires long-term use of immunosuppressive agents, which brings complications sometimes fatalthe. Since the1980s, scientists first proposed the concept of "tissue engineering", a large number of tissue defects and organ failure patients had been treated.Tissue engineering by the U.S. National Science Foundation in1987, the application of cell biology, biomaterials and engineering principles, research and development for biological activity alternatives to repair or improve human lesions tissue or organ structure and function.This topic is the study of the prosthesis alternatives in the mandible tumor lesions during surgery to modeling technology based on tissue engineering and rapid prototyping. Against the concept of tissue engineering, this project through reverse engineering, UG secondary development, as well as biomedical materials, and other methods to achieve the manufacture of prosthetic substitutes. The contents of this subject have the following four aspects:(l).Collect the patient’s CT data. Reverse modeling, based on CT imaging applications with medical software (Mimics,10.01) and reverse software (Geomagic Studio10).Trying to restore the true three-dimensional model of the patients jaw, for following artificial organizational modeling technology to reduce the error and laid a good foundation.(2).Through the understanding of disease pathogenesis and common onset position, as well as within the bone micro-structure. Use the software according to a common location of interception of the appropriate location, and to simplify the model shape of the cutting. Summary of the model the internal structure of artificial bone tissue at home and abroad, put the author’s own modeling thinking.(3). Study the secondary development of the language in UG Advanced Simulation module divided into hexahedral mesh and extract information of nodes and unit.Through of UG Open GRIP and C++mixed language programming, the core of the modeling process is the GRIP, the programming method to construct three-dimensional model of artificial bone within the organization, improve the modeling efficiency.(4).Use of rapid prototyping technology, processed the aforementioned model into entities. And the aforementioned model as a mold, to hydroxyapatite as a prosthetic material, to create a prosthesis of the bioactive materials. Finally, there is a performance analysis for the prosthesis alternatives.