| BackgroundWith the progress of global industrialization, cardiovascular and cerebrovasculardiseases have become a major cause of human death, and a heavy disease burden tosociety. While the mortality rate caused by hypertension cardiovascular disease havebeen discharged to the first all diseases mortality. Hypertension is the world’s longhistory, widely popular range of serious harm, but extremely concealed a cardiovasculardisease. With the continuous development of medical technology, treatment ofcontinuous improvement, constantly updated types of drugs, hypertension have madegreat progress in the treatment field. However, advances in medical technology and noteffectively curb the rapid growth of the progress of the disease in patients withhypertension and hypertension incidence, prevalence of hypertension in recentyears, with economic development, improvement of livingstandards and urbanization and aging many reasons, has been a growing trend, hasbecome one of the most important worldwide public health problem. China’sannual expenses spent on cardiovascular disease is about300billion yuan, of which thedirect medical costs of hypertension is about30billion yuan. Therefore, the study ofdisease-related causes of hypertension, risk factors such as hypertension prevention andtreatment become a research focus.In recent years, the world and actively carry out surveysand epidemiological studies on hypertension, based on the results of these studies inorder to develop and constantly revised prevention guidelines to improve the diagnosisand treatment of hypertension knowledge and ability of medical personnel to help highblood pressure high-risk groups, patients with effective prevention, control ofhypertension occurrence and development. However, hypertension as anenvironmental and genetic factors play a role in the disease, its etiology and pathogenesis is very complex. The rapid growth of advances in medical technology didnot able to effectively curb the progress of the disease in patients with high bloodpressure and hypertension incidence. Therefore, the study of disease-related causesof hypertension, risk factors such as hypertension prevention andtreatment become a research focus.In this study, epidemiological survey methods, Suzhou Industrial Park residentquestionnaire and physical measurements to measure understanding of the areas of thebody and the relationship between blood pressure and hypertension related factors.Purpose1. Understand the Suzhou industrial park residents blood pressure distribution, therelationship between the body measurements and blood pressure measurements, find isthe most closely related indicators with hypertension, high blood pressure risk groups toprovide the most suitable for screening of predictors.2. Understanding of the relevant factors of hypertension in the Suzhou IndustrialPark, to find and control measures to reduce the prevalence of hypertension in theregion to provide clues.Methods1. Suzhou industrial park resident`s blood pressure measured value analysis of therelationship between body measurementsBy the method of queue and packet cluster random sampling method,2007-2008,the Suzhou industrial park, seven community35-74years the population of permanentresidents as the research object, hypertension epidemiological investigation and physicalexamination, including general demographic characteristics, health knowledge level,behavior habits. Physical examination project: height, weight, waist circumference, hipcircumference, blood pressure levels. To client by gender, age, weight, waistcircumference, WHR,, by T test and variance analysis and comparison between groupsof blood pressure level difference, in ROC curves reflect the body measurement indexto predict the AUC of high blood pressure, the best point of tangency, sensitive andspecific degrees.2. Logistic regression analysis of influencing factors of hypertension in the SuzhouIndustrial ParkBaseline analysis of influential factors on hypertension (P<0.001) in the further analysis to study the effect of different lifestyle residents prevalence ofhypertension univariate analysis, to exclude the influence of otherfactors, using multivariate analysis hypertension factor.Rate calculationprocess or constitute a relatively than using test mean comparison T test,univariate analysis of the main evaluation index for the RR value, multivariate analysisusing non-conditional Logistic regression equation.All statistical tests were two-sided test, P <0.05that is considered statisticallysignificant.Results1. Baseline characteristics of the Suzhou Industrial Park surveySurvey of1905residents (787males and1female118). Follow-up period,131cases of new-onset hypertension cases, men and women were58cases,73cases, thecumulative incidence of7.4%and6.5%respectively. In addition to age, BMI, familyhistory of hypertension, occupational sedentary habits, physical exercise, and thecumulative incidence of other differences in baseline indicators of male andfemale subjects were statistically significant (P <0.01).2. Suzhou Industrial Park resident`s hypertension influencing factorsUnivariate analysis showed that: Relative to baseline non-oil dietgroup, baseline high fat diet group had a higher cumulative incidence ofhypertension (11.3%VS1.4%), RR (95%CI) was8.66(1.17-64.30) difference wasstatistically significant (P <0.05). Relative to baseline light salt dietgroup, baseline high-salt diet group had a higher cumulative incidence ofhypertension (6.7%VS2.6%), RR (95%CI) was3.89(1.39-10.98) difference wasstatistically significant (P <0.05). Relative to baseline normal, baseline overweight havea higher cumulative incidence of hypertension (8.6%VS5.4%), RR95%CI1.54(1.46-5.09), the difference was statistically significant (P<0.05); baseline obesity group relative to the control group at baseline had ahigher cumulative incidence of hypertension (9.0%VS5.8%), RR95%CI1.61(1.45-5.80), the difference was statistically significant (P <0.05).Multivariate Logistic regression analysis showed that gender, high salt and highoil diet, sedentary work, exercise, BMI, smoking, alcohol consumption included in thefinal model. Excluding the impact of confounding factors, overweight and obesity are the main factors affecting hypertension BMI (OR=1.422,95%CI=1.107-1.826).Conclusion1. The blood pressure level is associated with sex, age, with BMI for high bloodpressure, preliminary screening of high-risk groups, but the prediction effect ofhypertension needs further confirmation.2. Overweight and obesity are the main risk factors of hypertension... |
PDF Full Text Request