Study On Lifestyle And TCM Syndrome Types In Young And Middle-aged Overweight/obese Patient

ObjectiveExplore the potential relationship between different lifestyles and overweight/obesity in middle-aged and young people,analyze the distribution characteristics of syndrome types in middle-aged and young people with overweight/obesity,and provide data support and theoretical basis for the prevention and traditional Chinese medicine treatment of overweight/obesity in middle-aged and young people.MethodsBy means of retrospective study,the population who visited the TCM lipid-lowering clinic of the Cardiovascular Department of Xiyuan Hospital from September 2021 to February 2023 were included,and their demography information,measurement indicators,four diagnostic information and test indicators were extracted.After verifying the qualified object information,enter it into Excel 2016 to establish the original database,and use SPSS 25.0 software for statistical analysis.Using linear regression method to analyze the relationship between different lifestyles and subjects’ BMI,and screen out possible independent risk factors for overweight/obesity in middle-aged and young people;Based on existing guidelines and expert experience,traditional Chinese medicine syndrome types of overweight/obesity are mainly divided into four types:spleen deficiency and dampness excess,liver and kidney yin deficiency,gastrointestinal excess heat,and qi stagnation and blood stasis.Relevant statistical methods are used to study the distribution of syndrome types in middle-aged and young overweight/obesity populations,and to explore the differences in gender,age,comorbidities,laboratory examination indicators,and other aspects of different syndrome types;Exploring the distribution of overweight/obesity syndrome types in middle-aged and young people using principal component analysis and cluster analysis methods,in order to supplement existing guidelines.Results1.General information:A total of 561 participants were included in this study,with 398 females and 163 males.The median age was 40 years old,and the median body mass index(BMI)was 27.64 kg/m2.2.Correlation between overweight/obesity and multiple risk factors such as lifestyle in middle-aged and young people:Linear stepwise regression analysis was used to analyze the correlation between BMI and multiple risk factors such as lifestyle in the middle-aged and young people.In the final regression equation,the significance of seven independent variables,namely gender,preference for ice water,preference for frying,night snack habit,preference for sweet and salty foods,and age stratification,P<0.05,and the regression coefficients B were 2.938,1.136,0.783,0.683,0.908,0.803,and-0.466,respectively.According to regression coefficient analysis,males,those who prefer drinking ice water,those who prefer frying,those who often eat night snacks,those who prefer sweet food,those who prefer salty taste,and those who are younger may be risk factors for overweight/obesity in middle-aged and young people.3.Distribution of overweight/obesity syndrome types in middle-aged and young people:A total of 478 overweight/obesity patients were included for traditional Chinese medicine syndrome analysis.The results showed that the spleen deficiency and dampness excess syndrome was the most frequent syndrome type,with 194 cases accounting for 40.6%.The frequency of liver and kidney yin deficiency syndrome,gastrointestinal excess heat syndrome,and qi stagnation and blood stasis syndrome was 18.0%,20.9%,and 20.5%,respectively.The proportion of spleen deficiency dampness excess syndrome(46.8%)in male patients was significantly higher than that in female patients(37.6%),and the proportion of gastrointestinal excess heat syndrome(25.5%)in female patients was significantly higher than that in male patients(11.5%),P=0.005.The waist circumference(92.5cm)of patients with gastrointestinal excess heat syndrome is significantly lower than the other three syndrome types,P=0.028.The test results for comorbidities showed that the proportion of liver and.kidney yin deficiency syndrome(22.7%)in middle-aged and young overweight/obese patients with hypertension was significantly higher than that in patients without hypertension(15.3%),P=0.042;The proportion of spleen deficiency and dampness excess syndrome(45.8%)in middle-aged and young overweight/obese patients with combined fatty liver disease was significantly higher than that in patients without combined fatty liver disease(34.4%),P=0.019.The test results of the relationship between lifestyle and syndrome types showed that among patients who frequently eat puffed food,the proportion of Qi stagnation and blood stasis syndrome(30.0%)was significantly higher than that of patients who do not frequently eat puffed food(18.3%),with P=0.046.The frequency of breakfast for patients with gastrointestinal excess heat syndrome is significantly lower than the other three syndrome types,P=0.029.4.Cluster analysis of syndromes in middle-aged and young overweight/obese patients:The results of cluster analysis showed that 34 symptoms were ultimately clustered into 5 categories.Based on guidelines and clinical experience,the syndrome groups were named as liver depression and spleen deficiency syndrome,spleen deficiency and dampness excess syndrome,phlegm and blood stasis mutual accumulation syndrome,heat deficiency and yin syndrome,and spleen and kidney yang deficiency syndrome,with frequencies of 54,146,51,105,and 122,respectively.Conclusions1.Men,who prefer drinking ice water,enjoying flying,often eating night snacks,liking sweet food,liking salty taste,and being young may be risk factors for overweight/obesity in middle-aged and young people.2.Spleen deficiency and dampness excess syndrome is the most common traditional Chinese medicine syndrome type among middle-aged and young overweight/obese patients,and the proportion of gastrointestinal excess heat syndrome is also higher in female patients.There are statistically significant differences in waist circumference,whether hypertension is present,whether fatty liver is present,whether puffed foods are frequently consumed,and the frequency of breakfast among different syndrome types.The proportion of patients with liver and kidney yin deficiency syndrome combined with hypertension is higher,while the proportion of patients with spleen deficiency and dampness excess syndrome combined with fatty liver is higher.Patients with Qi stagnation and blood stasis syndrome have a higher frequency of eating puffed food,while patients with gastrointestinal excess heat syndrome have a lower frequency of eating breakfast.3.Overweight/obesity in middle-aged and young people presents a characteristic of multiple disease locations and a mixture of deficiency and excess.Its pathogenesis is mainly due to spleen dysfunction,involving yin deficiency,liver depression,kidney deficiency,water dampness,phlegm and yin,blood stasis,and other aspects.Overall,overweight/obesity in middle-aged and young people presents a characteristic of being overweight and obese,with a tendency to be overweight and obese.