Detection Of Serum D-dimer And Its Clinical Significance In Hypertensive Intracerebral Hemorrhage

Objective: Hypertensive intracerebral hemorrhage had the high morbidity and highmortality.Pathological mechanisms of hypertensive cerebral hemorrhage neurologicaldamage the medical profession has been the focus of attention. This study of patients withhypertensive intracerebral hemorrhage D-dimer determined to explore the relationshipbetween plasma D-dimer and time, amount of bleeding, nerve damage degree ofrecovery in patients with hypertensive intracerebral hemorrhage.Methods: Select October2012to October2013in our hospital neurology hospital102cases of hypertensive cerebral hemorrhage, within24hours of onset, including56malesand46females;40to88years old (63.18±11.27), admission blood pressure is150-210/90-120mmHg. After admission, the patient’s family to explain the situation indetail to inform the families of the sick patient’s condition and the need to inform theclinical study, the consent of the patient’s family agreed that in the first day afteradmission and the14day morning fasting blood tests DDI plasma levels, and activelycarry out dehydration, reducing intracranial pressure, Anti-infection treatment, with52cases of healthy controls were carried out to compare.Results:1.The102patients in the first day, DDI content of the first14days in the controlgroup of three sets of data were compared, HICH patients on day1compared with thehealthy control group differences in levels of DDI have statistically significant (P <0.01),HICH patients on the first day higher than the healthy control group DDI content. HICH14d onset patients compared with the healthy control group the difference was notstatistically significant DDI content (P>0.05);2.According to the102cases of bleeding in patients with different data divided into three groups, a small amount of bleeding group (<10ml), in the amount of bleeding group (10~30ml), massive bleeding group (>30ml) and all four sets of data in the case group D-twocorrelation analysis dimer levels and the amount of bleeding derived regression equation,analysis of variance and regression, P <0.05;3.Depending on the extent of nerve damage restoration will draw53patients were dividedinto two groups, two groups were compared DDI content abnormal rate, derived P <0.05；4.Data for this study were using spss statistics17.0statistical package for data analysis.Conclusion:1.DDI content HICH early onset patients increased.2. DDI content HICH amount of bleeding in patients with a positive correlation linearrelationship.3.DDI content HICH can be used as an indicator of the patient’s neurological functionrecovery.