| 1ObjectiveCombing the development process of clearing heat and resolving phlegm method; clearing up the connotation and denotation of clearing heat and resolving phlegm method; summing up the regularity application of clearing heat and resolving phlegm method; clearing the content category, adaptation syndrome and prescription of clearing heat and resolving phlegm method. Making analysis of the combination method and clarifying the ancient and modern clinical application rule.2Content2.1The origin and development of clearing heat and resolving phlegm methodAccording to the time sequence, clear up ancient physicians’discussed, pharmacy, medical records, to explore the origin, inheritance, innovation of the method, and summarizes the characteristics and clarify the use of clearing heat and resolving phlegm method.2.2The connotation and extension of clearing heat and resolving phlegm methodThrough the longitudinal combs, horizontal comparison, and comprehensive analysis to definite the connotation and extension of clearing heat and resolving phlegm method. To make the concept clear and easy to understand and use.2.3Representative prescription and use of clearing heat and resolving phlegm methodAccording to the meaning of clearing heat and resolving phlegm method, to collect, comparison and analysis ancient and modern medical theory, representative prescription and conciliate. Clarifying clearing heat and resolving phlegm method representative prescription adaptation syndrome and prescription compatibility rules.3Methods 3.1Methods of Documentary Information Science(1)Ancient literature:Collect the document literature about clearing heat and resolving phlegm from the literature of medical classic, diagnostic, prescription, herbal, clinical and consilia, by reference books such as’San Bai Zhong Yi Ji Lu’ and’Zhong Guo Yi Ji Da Ci Dian’. At the same time put the’phlegm’as the term for full-text retrieval, screening’phlegm’ and’phlegm heat’related information by the ’Chinese Pharmacopoeia’(the fourth edition) and further analysis and sorting.(2)Modern reference books: collecting and collating relevant terms from ’Dictionary Of Traditional Chinese Medicine’,’Differential Diagnosis Of Traditional Chinese Medicine Syndromes’,’Differential Diagnosis Of Traditional Chinese Medicine Symptoms’,‘The People’s Republic of China national standard clinical diagnosis and treatment of traditional Chinese medicine’,’Dictionary Of Prescriptions Of Traditional Chinese Medicine’and so on.(3)Modern journal literature: collecting theory, clinical, experimental papers mainly based on CNKI, VIP, Wan Fang database and put’phlegm heat’,’heat phlegm’,’phlegm fire’as the key words.3.2Methods of theory researchBased on the research results and applied on the methods of theoretical analysis, induction and interpretation to define the connotation and extension of the definition of’clearing heat and resolving phlegm method’and clarify the meaning and usage of it; discriminate some similar and relevant terms; analysis and summary of ancient physicians treating heat phlegm academic characteristics; compare clearing heat and resolving phlegm prescription and selecting the representative prescription to analyzes.4Results4.1Clarified the origin of clearing heat and resolving phlegm methodThe Qin and Han Dynasties period The embryonic stage of the period of clearing heat and resolving phlegm method. According to the existing literature, was not yet clearly put forward the concept of‘phlegm’, but there are drugs and prescription records. Such as Tao Hong jing’s’Shen Nong Ben Cao Jing Ji Zhu’, recorded Radix Scutellariae, Fritillaria and other drugs can cure phlegm heat;’Shang Han Za Bing Lun’which has the efficacy of clearing heat and resolving phlegm such as’xiaoxianxiongtang’,’jupizhurutang’and so on.Wei Jin to Sui and Tang Dynasties period’Zhu Bing Yuan Hou Lun’clearly put forward the’heat phlegm syndrome’, and discusses its etiology and pathogenesis. It’s the earliest introduction to the theory. There are the record of about experience of diagnosis and treatment of phlegm in other books, and it has become a source of clinical application of phlegm heat later.Song Jin and Yuan Dynasties period Zhu Danxi, Wang Gui and other doctors clarified the cause, pathogenesis, treatment and prescription of phlegm heat syndrome. Pointing out that the six exogenous pathogenic factors, diet and emotional stagnation are the main factors. Creating prescriptions of clearing heat and resolving phlegm—’wendantang’,’mengshiguntanwan’and so on.Ming and Qing Dynasties period Clearing heat and resolving phlegm method is more widely used in the treatment of clinical disease, and the medicine is more abundant. In particular,’Hong Lu Dian Xue’and’Tan Huo Zhuan Men’clarify the treatment of phlegm fire and interpret the’qingrexiehuoyangyinfa’deeply.4.2Charified the connotation and extension of clearing heat and resolving phlegm methodClearing heat and resolving phlegm method, refers to clearing heat and resolving phlegm combined with the use, to treat the phlegm and heat syndrome. According to the specific pathogenesis of phlegm heat syndrome, these are the clinical treatment:Clearing heat and resolving phlegm and ventilating the lung method it is for the treatment of phlegm heat obstructing lung and Phlegm heat closed lungs. Treating cough, chest tightness; or cough with thick yellow phlegm; or chest pain, shortness of breath; or restlessness, fever, thirst; or constipation, short yellow urine; red tongue and yellow thick tongue coating, slippery and fast pulse.Clearing heat and resolving phlegm and inducing resuscitation method it is for the treatment of phlegm heat closed to the insane such as beating and destroy; or incognizant the relationship; or high fever; red tongue and yellow thick tongue coating, slippery and fast pulse.Clearing heat and resolving phlegm and dispel melancholy method it is for the treatment of liver Qi stagnation and phlegm heat closed. Treating lateral thorax pain, irritability, insomnia, dizziness, headache, red tongue and yellow thick tongue coating, slippery and fast pulse.Clearing heat and resolving phlegm and relieving dizziness method it is for the treatment of phlegm and heat to liver wind agitation. Treating limbs tic, opisthotonus, even convulsion; or dizziness, headache, strabismus, lockjaw; red tongue and yellow thick tongue coating, slippery and fast pulse.Clearing heat and resolving phlegm and nourishing yin method it is for the treatment of yin deficiency and phlegm heat syndrome. Treating cough sputum less sticky; insomnia, heart palpitations; convulsions, spasm; loss of appetite; red tongue, fast pulse.Clearing heat and resolving phlegm and removing stasis method it is for the treatment of phlegm heat to nodule. Treating the nodule increases faster, heat, pain, push not to move; constipation, red tongue and yellow thick tongue coating, slippery and fast pulse.Clearing heat and resolving phlegm and harmonizing stomach method it is for the treatment of phlegm heat accumulating stomach. Treating shortness of breath, nausea, vomiting, thirst; or cough, constipation; red tongue and yellow thick tongue coating, slippery and fast pulse.Clearing heat and resolving phlegm and bowel-relaxing method4.3the representative prescription for clearing heat and resolving phlegm methodSelected14ancient and modern prescription resolving phlegm heat from’Yi Fang Ji Jie’,’Cheng Fang Qie Yong’,’Yi Fang Kao’,’Tang Tou Ge Jue’and so on. Discussed the efficacy, compatibility, addition and subtraction etc and according to medical records related to the basis, expound the law of clinical application.5ConclusionClearing heat and resolving phlegm method lay in some classics of traditional Chinese medicine, such as’Huang Di Nei Jing’,’Shen Nong Ben Cao Jing’and ’Shang Han Za Bing Lun’; Wei Jin to Sui and Tang Dynasties period, is the embryonic stage of the period of clearing heat and resolving phlegm method, at the same time accumulated clinical experience for the development of future; Song Jin and Yuan Dynasties period, is the period of construction method of clearing heat and resolving phlegm, innovation and development of etiology and pathogenesis, greatly promote the connotation of clearing heat and resolving phlegm theory; Ming and Qing Dynasties physicians inherited and summarized the thought of phlegm heat syndrome diagnosis and treatment, and focused on the diagnosis and treatment of yin deficiency and phlegm heat, and phlegm stagnation syndrome of in depth analysis; In modern times, clearing heat and resolving phlegm method is widely used in the treatment of many diseases. In the ancient and modern development, the overall focus on clinical deeply, but slightly in theory study.Based on the analysis of ancient and modern literature, the connotation of ’clearing heat and resolving phlegm method’, refers to clearing heat and resolving phlegm combined with the use, to treat the phlegm and heat syndrome. Through summarizing term for’clearing heat and resolving phlegm method’related terms, put forward eight extension: clearing heat and resolving phlegm and ventilating the lung method, clearing heat and resolving phlegm and inducing resuscitation method, clearing heat and resolving phlegm and dispel melancholy method, clearing heat and resolving phlegm and relieving dizziness method, clearing heat and resolving phlegm and nourishing yin method, clearing heat and resolving phlegm and removing stasis method, clearing heat and resolving phlegm and harmonizing stomach method, clearing heat and resolving phlegm and bowel-relaxing method.Based on the definition the connotation and extension of clearing heat and resolving phlegm method, to extracted14prescriptions from the ancient and modern clinical treatment of phlegm heat syndrome:qingqihuatanwan(Yi Fang Kao), dingchuantang(She Sheng Zhong Miao Fang), lingjiaogoutengtang(Tong Shu Shang Han Lun), qingjinsan(He Shi Xu Lao Xin Chuan), beimugualousan(Yi Xue Xin Wu), jupizhurutang(Jin Kui Yao Lue), xiaoluowan(Yi Xue Xin Wu), wendantang(San Yin Ji Yi Bing Zheng Fang Lun), chaihuxianxiongtang(Tong Shu Shang Han Lun), xiaoxianxiongtang(Shang Han Lun), angongniuhuangwan(Wen Bing Tiao Bian), dingxianwan(Yi Xue Xin Wu). To provide theoretical support for the clinical treatment of phlegm heat syndrome. |