Clinical Studies On Postoperative Olfactory Changes In Chronic Sinusitis Patients With Olfactory Dysfunction

Objective: Explore the relationship between the degree of recovery ofchronic sinusitis olfactory function and operation.Method: In October2014to December2014, Jilin UniversityChina-Japan cooperation Hospital treated48cases of chronic sinusitispatients with olfactory dysfunction, which excluded patients with fungalsinusitis and atrophic rhinitis and other diseases.28males and20females,aged24to57years, with an average age of40years old, polyps in19patients,29cases of patients without nasal polyps, there was no history ofprevious nasal surgery. All patients were treated by whole group or part ofEndoscopic sinus opening surgery. We took10kinds of odorous articlesfor daily use in the preoperative and postoperative1month respectively.The cotton swab moistened with test items placed at a distance of oneside of the nasal cavity at about1~2cm, and patients needed to holddown the opposite side of the nose at the same time, also patient wasasked to breath slowly and evenly, approximately2to3times. Patientswere detected according to the concentration of test products from low tohigh in the order, scored the sence of smell by visual analog scale (VAS)in the preoperative and postoperative1month respectively, thencompared their sense of smell changes. We use the application of SPSS 18.0software for statisical analysis. All patients received regularEndoscopic cleaning, nasal corticosteroids medication, conventionalanti-inflammatory anti-infection disposal and so on.Results:1. There are45cases (94%) with varying degrees ofimprovement after surgery, and23cases (51%) with significantimprovement,16cases (36%) improved,6cases (13%) returned tonormal,3cases (6%) had not improvement at all, and no readmehyposmia after surgery.2. Overall patients before surgery without nasal polyps smell have a littleserious olfactory dysfunction than patients with nasal polyps, comparedthe two types of patients’ improvement of olfactory dysfunctionpostoperatively with preoperative contrast. In significant and returned tonormal, the improvement of olfactory dysfunction of patients withoutnasal polyps postoperatively is slightly better than the polyps, p<0.05,andthis have the statistics significance.3. Preoperative patients over the age of40are more concentrated inmoderate and severe Olfactory dysfunction, patients below the age of40are more concentrated in the mild to moderate olfactory dysfunction,compared the two types of patients’ improvement of olfactorydysfunction postoperatively with preoperative contrast. In significant andreturned to normal, the improvement of olfactory dysfunction of patientsbelow the age of40is better than patients over the age of40, p<0.05,and this have the statistics significance.4. In the test, preoperative olfactory dysfunction in male patients isslightly more than in female patients, and we compare the two types ofpatients’ improvement of olfactory dysfunction postoperatively withpreoperative contrast, there is no significant difference of olfactorydysfunction improvement postoperatively beteen male patients andfemale patients.Conclusion:1. Chronic sinusitis patients with olfactory dysfunction mayhave different degrees of improvement in olfactory function afterendoscopic sinus surgery.2. Nasal polyps factors have an effect on patients with postoperativedysosmia recovery,it is showed that the olfactory recovery of patientswith nasal polyps is worse than patients without nasal polyps.3. Age factors have an effect on patients with postoperative dysosmiarecovery,it is showed that the younger patients’ olfactory recovery isbetter than older patients.4. Gender factors have no obvious effect on patients with postoperativedysosmia recovery.