A Retrospective Study Of The Related Factors Of Intracranial Infection After Operation In The Neurosurgery And Perioperative Intervene Management

BackgroundIn recent years, more and more patients underwent neurosurgery craniotomy. Surgical personnel and technology are increasingly sophisticated, but it still does not prevent the intracranial infection rates from continuing to rise. About the risk factors that can lead to intracranial infection after craniotomy, a number of clinical medical workers conducted a rigorous statistical analysis of the patients in their own hospitals. As the environment around the operating room, medical personnel, as well as hospital environment are different, so different studies have reported different conclusions. In order to obtain more representative and universal conclusions, more and more researchers are required to take part in the study, and to develop a series of more reasonable and genenral strategies to prevent and control the intracranial infection after aseptic craniotomy.ObjectiveTo analyze the relevant factors that might cause intracranial infection after aseptic craniotomy, and accordingly to develop a series of rational prevention and control strategies based on the analysis results.MethodAccording to this study, from July 2011 to June 2014,573 cases of aseptic craniotomy were retrospectively analyzed using medicinal statistical methods, the relevant factors that might cause intracranial infections:indwelling drainage tube, postoperative cerebrospinal fluid leakage, operative time, surgical site, preoperative underlying disease such as diabetes, hypertension, pulmonary infection, surgery preconscious disorders, postoperative hormone theropy, type of surgery, gender and age, were statistically analyzed. Hence based on the analysis results, some prevention strategies for postoperative intracranial infection,such as nursing, nutritional support, and antibacterial drug use, were planed.Result22 cases out of 573 of intracranial infection occured after aseptic craniotomy, so the infection rate was 3.8%. According to univariate analysis results:the intracranial infection rate with preoperative diabetes was higher than those without diabetes, and the same with the intracranial infection rate of postoperative cerebrospinal fluid leakage, postoperative indwelling drainage tube, surgery duration longer than 4 hours or patients older than 60 years. The above differences were statistically significant (P<0.05). On the other hand, the results of this study did not confirm that the surgical site, preconscious disorders, postoperative hormone, type of surgery, preoperative hypertension, pulmonary infection, and gender had a significant effect on intracranial infection rate after aseptic craniotomy (P>0.05).ConclusionThe surgical site, duration of surgery time, postoperative cerebrospinal fluid leakage, indwelling drainage tube, preoperative diabetes and age are risk factors of postoperative intracranial infection.Preconscious disorders, postoperative hormone, type of surgery, preoperative hypertension, pulmonary infection, gender had no significant effects on the post-craniotomy intracranial infection.Enhance aseptic techniques and managements, especially improve the operation methods.