A Preliminary Study On The Living Maggot Therapy In The Treatment Of Chronic Diabetic Foot Ulcer Wound

Objective: chronic diabetic foot ulcer is characterized by long duration, poor curative effect and frequent concurrent infection; long-term anti-infective therapy can cause the body insensitive to antibiotics. This study intends to evaluate a new kind of biological therapy- the curative effect of living maggot debridement on chronic diabetic foot ulcer.Methods:the study selects the subject from the patients with protracted course of diabetic foot ulcer from July 2013 to November 2013 and other conservative treatments are in vain. Select qualified 14 cases and exclude those unqualified cases, inform their families of the purpose and process of this clinical study, illustrate the basic research methods, randomly divide the patients who are willing to participate in the study. The patient with living maggot debridement is the experimental group; while the patient with conventional dressing therapy is the control group. Two groups of patients go to the outpatient service to change dressings and record the wound recovery situation, and take their secretion to culture the bacteria. Check the number of maggot in the wound of the living maggot debridement group, and compare it with the last time. The control group has routine dressing change. When necessary, adopt the surgical debridement. Take the negative time, growth and healing time of granulation wound as the evaluation index. Use SPSS20.0 to count and analyze the data, combine its accompanying disease to deeply analyze the relationship between the treatment of Wuguchong and wound healing. In this study, two-sided test P<0.05 will be regarded as significantly statistical difference.Results:1. The real effective cases of this study are 13, the maggot debridement treatment group consists of 7 people, while the conventional dressing treatment group consists of 6 people, and the baseline information of two groups’ data is consistent. 2. The time to bacterial negativity of the maggot debridement treatment group is obviously less than that of the conventional treatment group with statistical significance(P<0.05). 3. The occurrence time of granulation tissue of the maggot debridement treatment group is obviously less than that of the conventional treatment group with statistical significance(P<0.05). 4. The wound healing time of the maggot debridement treatment group is obviously less than that of the conventional treatment group with statistical significance(P<0.05)Conclusion: living maggot biological debridement is an effective method for chronic diabetic foot ulcer wound, whose efficacy is better than the conventional surgical treatment.