Objective:This study used tonifying kidney recipe on ovulation induction of follicular unruptured follicle syndrome (LUFS) patients stimulation cycles intervention, to observe the clinical effect of the method, and to explore its possible mechanism, so as to provide clinical reference in TCM treatment of LUFS caused by infertility, ovulation period for relapsed LUFS patients seeking a safe, effective and cheap treatment method.Methods:40 patients with luteinized unruptured follicle syndrome were randomly divided into two groups,20 cases in the treatment group, Yishen ovulation +HCG treatment; the control group of 20 cases, using a simple HCG treatment. Comparison of two groups of LUF cycle ovulation rate, recurrence rate, pregnancy rate, clinical symptoms of TCM score, basal body temperature of BBT high temperature phase graded, and to explore the mechanism of Bushen Tongluo Decoction in prevention of brief stimulus cycle LUF recurrence. At the same time, the patients were observed the treatment cycle basic sexual hormone level (LH) and correlation between urinary LH peak and LUFS recurrence.Results:the treatment group included 20 patients, a total of 54 cycles,34 cycles of normal ovulation, the ovulation rate was 62.96%; the control group included 20 patients, a total of 53 cycles,20 cycles of normal ovulation, the ovulation rate was 37.74%; the treatment group 6 cases of pregnancy, the pregnancy rate was 30%, control group L cases of pregnancy, pregnancy rate of 5%. Ovulation rate and pregnancy rate in the treatment group were higher than those in the control group, the difference was statistically significant (P<0.05).54 cycles of the treatment group included,20 periodic recurrence period, the recurrence rate is 30.04%; the control group included 53 period,33 period recrudescent cycle, the recurrence rate is 62.26%. The treatment group the recurrence rate is lower than that of the control group, the difference was statistically significant (P<0.05). The two groups before treatment of TCM symptom score showed no statistical significance (P>0.05), after treatment, two groups of TCM symptoms integral were statistically significant (P<0.01). The treatment group before and after treatment of TCM symptom score were statistically significant (P<0.01), the control group before and after treatment of TCM symptom score showed no statistical significance (P>0.05). Judging index of TCM symptoms curative effect index, the patients in the two groups were statistically significant (P<0.05). The two groups before treatment of BBT high temperature phase HPS score showed no statistical significance (P>0.05), the two groups after treatment of BBT high temperature phase HPS scores were statistically significant (P<0.01). The treatment group before and after treatment of BBT high temperature phase HPS scores were statistically significant (P<0.01), the control group before and after treatment of BBT high temperature phase HPS score showed no statistical significance (P>0.05).Conclusion:the use of kidney ovulation party intervention, happen again, can effectively prevent the LUFS, to improve the ovulation rate, effectively reduce the incidence of corpus luteum insufficiency; improve the clinical pregnancy rate of patients with infertility caused by western medicine, make up the high ovulation rate, low pregnancy rate, and reduced the incidence of complications, use more secure. At the same time kidney ovulation party with Bushen Huoxue, Shugan helps the eggs for the law, so that the body to achieve a balance of yin and Yang, Qi and blood flow, viscera function coordination, clinical symptoms and syndromes of traditional Chinese medicine can significantly improve the patient’s. In addition, in patients with LUFS during the treatment of follicular development and dynamic monitoring of LH levels, recurrence in a certain extent can indicate the LUF cycle, is conducive to take relevant measures as soon as possible, to prevent LUF periodic. |