"Dispersion Index" To Evaluate The Prognosis Of ARDS

[Abstract] Objective To observe various causes lead to Acute Respiratory Distress Syndrome, ARDS need a invasive ventilation treatment, setting up the ventilation parameters in different levels of FiO2 and PEEP corresponding blood gas in the changes of arterial blood oxygen saturation and oxygenation index, the relationship between the patients survive and successful off tube in 28 days, so as to analyze PaO2÷(FiO2×PEEP) as "dispersion index" to evaluate clinical value of the prognosis of patients with ARDS. Methods To choice 100 patients between July 2014 and July 2013 in our ICU (EICU and MICU) treated by noninvasive or invasive ventilator support treatment of ARDS, record the parameters of the ventilator support during treatment and corresponding blood gas index, and analysis correlation with primary disease and prognosis in patients. Compare "dispersion index" and oxygenation index level correlation and guidance value judgment short-term prognosis of 28 days. Results "Dispersion index"is significantly related with the 28-day mortality in patients with, after treatment with ventilator support, if it continues to less than 256.4±6.4 (Mean±SD), which is indicated in patients with high mortality rate. Progression in patients with 4 days after the change trend of the numerical and oxygenation index in its predictions 28-day mortality in patients with AUC is higher, and Logistic regression analysis P values<0.05, with statistical significance. And if "dispersion index" lasting> 400 when offline more likely. Conclusion Ventilator support is a foundation treatment for ARDS patients. Monitoring "dispersion index" can preliminarily judge the severity of patients, dynamic observation of the variation tendency could judge the prognosis of patients with ARDS, and it has certain advantages than the oxygenation index for prognosis as offline or death judgment.